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3h9u

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==S-adenosyl homocysteine hydrolase (SAHH) from Trypanosoma brucei==
==S-adenosyl homocysteine hydrolase (SAHH) from Trypanosoma brucei==
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<StructureSection load='3h9u' size='340' side='right' caption='[[3h9u]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<StructureSection load='3h9u' size='340' side='right'caption='[[3h9u]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3h9u]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H9U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3H9U FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3h9u]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H9U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3H9U FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SAHH, Tb11.01.1350 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5691 Trypanosoma brucei])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosylhomocysteinase Adenosylhomocysteinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.3.1.1 3.3.1.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3h9u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h9u OCA], [https://pdbe.org/3h9u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3h9u RCSB], [https://www.ebi.ac.uk/pdbsum/3h9u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3h9u ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3h9u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h9u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3h9u RCSB], [http://www.ebi.ac.uk/pdbsum/3h9u PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q383X0_TRYB2 Q383X0_TRYB2]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h9/3h9u_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h9/3h9u_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3h9u ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Adenosylhomocysteinase]]
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[[Category: Large Structures]]
[[Category: Trypanosoma brucei]]
[[Category: Trypanosoma brucei]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Arrowsmith CH]]
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[[Category: Berg, S Van Den.]]
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[[Category: Berglund H]]
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[[Category: Berglund, H.]]
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[[Category: Bountra C]]
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[[Category: Bountra, C.]]
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[[Category: Collins R]]
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[[Category: Collins, R.]]
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[[Category: Edwards AM]]
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[[Category: Edwards, A M.]]
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[[Category: Flodin S]]
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[[Category: Flodin, S.]]
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[[Category: Flores A]]
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[[Category: Flores, A.]]
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[[Category: Graslund S]]
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[[Category: Graslund, S.]]
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[[Category: Hammarstrom M]]
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[[Category: Hammarstrom, M.]]
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[[Category: Johansson A]]
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[[Category: Johansson, A.]]
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[[Category: Johansson I]]
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[[Category: Johansson, I.]]
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[[Category: Karlberg T]]
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[[Category: Karlberg,T.]]
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[[Category: Kotenyova T]]
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[[Category: Kotenyova, T.]]
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[[Category: Kotzsch A]]
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[[Category: Kotzsch, A.]]
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[[Category: Kragh Nielsen T]]
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[[Category: Moche, M.]]
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[[Category: Moche M]]
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[[Category: Nielsen, T Kragh.]]
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[[Category: Nordlund P]]
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[[Category: Nordlund, P.]]
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[[Category: Nyman T]]
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[[Category: Nyman, T.]]
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[[Category: Persson C]]
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[[Category: Persson, C.]]
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[[Category: Sagemark J]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Schueler H]]
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[[Category: Sagemark, J.]]
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[[Category: Schutz P]]
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[[Category: Schueler, H.]]
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[[Category: Siponen MI]]
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[[Category: Schutz, P.]]
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[[Category: Thorsell AG]]
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[[Category: Siponen, M I.]]
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[[Category: Tresaugues L]]
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[[Category: Thorsell, A G.]]
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[[Category: Van Den Berg S]]
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[[Category: Tresaugues, L.]]
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[[Category: Weigelt J]]
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[[Category: Weigelt, J.]]
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[[Category: Welin M]]
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[[Category: Welin, M.]]
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[[Category: Wisniewska M]]
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[[Category: Wisniewska, M.]]
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[[Category: Hydrolase]]
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[[Category: Nad]]
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[[Category: Nad co-factor complex]]
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[[Category: One-carbon metabolism]]
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[[Category: Sgc]]
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[[Category: Sgc stockholm]]
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[[Category: Structural genomic]]
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[[Category: Structural genomics consortium]]
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Current revision

S-adenosyl homocysteine hydrolase (SAHH) from Trypanosoma brucei

PDB ID 3h9u

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