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3hl2

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==The crystal structure of the human SepSecS-tRNASec complex==
==The crystal structure of the human SepSecS-tRNASec complex==
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<StructureSection load='3hl2' size='340' side='right' caption='[[3hl2]], [[Resolution|resolution]] 2.81&Aring;' scene=''>
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<StructureSection load='3hl2' size='340' side='right'caption='[[3hl2]], [[Resolution|resolution]] 2.81&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3hl2]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HL2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HL2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3hl2]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HL2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HL2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PLR:(5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL+DIHYDROGEN+PHOSPHATE'>PLR</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=TS6:MONOTHIOPHOSPHATE'>TS6</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.81&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SEPSECS, TRNP48 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLR:(5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL+DIHYDROGEN+PHOSPHATE'>PLR</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=TS6:MONOTHIOPHOSPHATE'>TS6</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-seryl-tRNA(Sec)_selenium_transferase L-seryl-tRNA(Sec) selenium transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.9.1.1 2.9.1.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hl2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hl2 OCA], [https://pdbe.org/3hl2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hl2 RCSB], [https://www.ebi.ac.uk/pdbsum/3hl2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hl2 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hl2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hl2 OCA], [http://pdbe.org/3hl2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hl2 RCSB], [http://www.ebi.ac.uk/pdbsum/3hl2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hl2 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SPCS_HUMAN SPCS_HUMAN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hl/3hl2_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hl/3hl2_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[Selenocysteine|Selenocysteine]]
 
*[[Selenocysteine synthase|Selenocysteine synthase]]
*[[Selenocysteine synthase|Selenocysteine synthase]]
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*[[TRNA|TRNA]]
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*[[Transfer RNA (tRNA)|Transfer RNA (tRNA)]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Palioura, S]]
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[[Category: Large Structures]]
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[[Category: Simonovic, M]]
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[[Category: Palioura S]]
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[[Category: Soll, D]]
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[[Category: Simonovic M]]
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[[Category: Steitz, T A]]
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[[Category: Soll D]]
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[[Category: Protein biosynthesis]]
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[[Category: Steitz TA]]
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[[Category: Protein-rna complex]]
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[[Category: Pyridoxal phosphate]]
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[[Category: Selenium]]
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[[Category: Selenocysteine]]
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[[Category: Sepsec]]
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[[Category: Transferase]]
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[[Category: Trnasec]]
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Current revision

The crystal structure of the human SepSecS-tRNASec complex

PDB ID 3hl2

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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