3hq1
From Proteopedia
(Difference between revisions)
(One intermediate revision not shown.) | |||
Line 1: | Line 1: | ||
==Crystal structure of Mycobacterium tuberculosis LeuA complexed with citrate and Mn2+== | ==Crystal structure of Mycobacterium tuberculosis LeuA complexed with citrate and Mn2+== | ||
- | <StructureSection load='3hq1' size='340' side='right' caption='[[3hq1]], [[Resolution|resolution]] 1.70Å' scene=''> | + | <StructureSection load='3hq1' size='340' side='right'caption='[[3hq1]], [[Resolution|resolution]] 1.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[3hq1]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3hq1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HQ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HQ1 FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | |
- | <tr id=' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hq1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hq1 OCA], [https://pdbe.org/3hq1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hq1 RCSB], [https://www.ebi.ac.uk/pdbsum/3hq1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hq1 ProSAT]</span></td></tr> |
- | < | + | |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
- | [ | + | [https://www.uniprot.org/uniprot/LEU1_MYCTU LEU1_MYCTU] Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Line 24: | Line 22: | ||
==See Also== | ==See Also== | ||
- | *[[2-isopropylmalate synthase|2-isopropylmalate synthase]] | + | *[[2-isopropylmalate synthase 3D structures|2-isopropylmalate synthase 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Mycobacterium tuberculosis H37Rv]] |
- | [[Category: Baker | + | [[Category: Baker EN]] |
- | [[Category: Koon | + | [[Category: Koon N]] |
- | [[Category: Squire | + | [[Category: Squire CJ]] |
- | + | ||
- | + | ||
- | + | ||
- | + | ||
- | + | ||
- | + | ||
- | + | ||
- | + |
Current revision
Crystal structure of Mycobacterium tuberculosis LeuA complexed with citrate and Mn2+
|