This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3ihl

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:47, 6 September 2023) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:3ihl.jpg|left|200px]]
 
-
<!--
+
==Human CTPS2 crystal structure==
-
The line below this paragraph, containing "STRUCTURE_3ihl", creates the "Structure Box" on the page.
+
<StructureSection load='3ihl' size='340' side='right'caption='[[3ihl]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3ihl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IHL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IHL FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-
{{STRUCTURE_3ihl| PDB=3ihl | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ihl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ihl OCA], [https://pdbe.org/3ihl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ihl RCSB], [https://www.ebi.ac.uk/pdbsum/3ihl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ihl ProSAT]</span></td></tr>
-
 
+
</table>
-
===Human CTPS2 crystal structure===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/PYRG2_HUMAN PYRG2_HUMAN] Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides.<ref>PMID:10899599</ref> <ref>PMID:16179339</ref>
-
 
+
== Evolutionary Conservation ==
-
==About this Structure==
+
[[Image:Consurf_key_small.gif|200px|right]]
-
3IHL is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IHL OCA].
+
Check<jmol>
-
[[Category: CTP synthase]]
+
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ih/3ihl_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ihl ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Arrowsmith, C H.]]
+
[[Category: Large Structures]]
-
[[Category: Berg, S Van Den.]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Berglund, H.]]
+
[[Category: Berglund H]]
-
[[Category: Bountra, C.]]
+
[[Category: Bountra C]]
-
[[Category: Collins, R.]]
+
[[Category: Collins R]]
-
[[Category: Edwards, A M]]
+
[[Category: Edwards AM]]
-
[[Category: Flodin, S.]]
+
[[Category: Flodin S]]
-
[[Category: Flores, A.]]
+
[[Category: Flores A]]
-
[[Category: Graslund, S.]]
+
[[Category: Graslund S]]
-
[[Category: Hammarstrom, M.]]
+
[[Category: Hammarstrom M]]
-
[[Category: Johansson, A.]]
+
[[Category: Johansson A]]
-
[[Category: Johansson, I.]]
+
[[Category: Johansson I]]
-
[[Category: Karlberg, T.]]
+
[[Category: Karlberg T]]
-
[[Category: Kotenyova, T.]]
+
[[Category: Kotenyova T]]
-
[[Category: Kotzsch, A.]]
+
[[Category: Kotzsch A]]
-
[[Category: Moche, M.]]
+
[[Category: Kragh Nielsen T]]
-
[[Category: Nielsen, T Kragh.]]
+
[[Category: Moche M]]
-
[[Category: Nordlund, P.]]
+
[[Category: Nordlund P]]
-
[[Category: Nyman, T.]]
+
[[Category: Nyman T]]
-
[[Category: Persson, C.]]
+
[[Category: Persson C]]
-
[[Category: Roos, A K.]]
+
[[Category: Roos AK]]
-
[[Category: SGC, Structural Genomics Consortium.]]
+
[[Category: Sagemark J]]
-
[[Category: Sagemark, J.]]
+
[[Category: Schueler H]]
-
[[Category: Schueler, H.]]
+
[[Category: Schutz P]]
-
[[Category: Schutz, P.]]
+
[[Category: Siponen MI]]
-
[[Category: Siponen, M I.]]
+
[[Category: Thorsell AG]]
-
[[Category: Thorsell, A G.]]
+
[[Category: Tresaugues L]]
-
[[Category: Tresaugues, L.]]
+
[[Category: Van Den Berg S]]
-
[[Category: Weigelt, J.]]
+
[[Category: Weigelt J]]
-
[[Category: Welin, M.]]
+
[[Category: Welin M]]
-
[[Category: Wisniewska, M.]]
+
[[Category: Wisniewska M]]
-
[[Category: Atp-binding]]
+
-
[[Category: Domain swapping]]
+
-
[[Category: Glutamine amidotransferase]]
+
-
[[Category: Ligase]]
+
-
[[Category: Nucleotide-binding]]
+
-
[[Category: Phosphoprotein]]
+
-
[[Category: Pyrimidine biosynthesis]]
+
-
[[Category: Sgc]]
+
-
[[Category: Sgc stockholm]]
+
-
[[Category: Structural genomic]]
+
-
[[Category: Structural genomics consortium]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 14 10:36:27 2009''
+

Current revision

Human CTPS2 crystal structure

PDB ID 3ihl

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3ihl"
Personal tools