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3ihi

From Proteopedia

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Current revision (07:47, 6 September 2023) (edit) (undo)
 
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<StructureSection load='3ihi' size='340' side='right'caption='[[3ihi]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
<StructureSection load='3ihi' size='340' side='right'caption='[[3ihi]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ihi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IHI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IHI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ihi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IHI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IHI FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.94&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3ihh|3ihh]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Tyms ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ihi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ihi OCA], [https://pdbe.org/3ihi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ihi RCSB], [https://www.ebi.ac.uk/pdbsum/3ihi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ihi ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ihi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ihi OCA], [https://pdbe.org/3ihi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ihi RCSB], [https://www.ebi.ac.uk/pdbsum/3ihi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ihi ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/TYSY_MOUSE TYSY_MOUSE]] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway (By similarity).
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[https://www.uniprot.org/uniprot/TYSY_MOUSE TYSY_MOUSE] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Thymidylate synthase]]
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[[Category: Ciesla J]]
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[[Category: Ciesla, J]]
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[[Category: Dowiercial A]]
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[[Category: Dowiercial, A]]
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[[Category: Fraczyk T]]
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[[Category: Fraczyk, T]]
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[[Category: Jarmula A]]
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[[Category: Jarmula, A]]
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[[Category: Rode W]]
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[[Category: Rode, W]]
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[[Category: Rypniewski WR]]
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[[Category: Rypniewski, W R]]
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[[Category: Sokolowska M]]
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[[Category: Sokolowska, M]]
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[[Category: Methyltransferase]]
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[[Category: Nucleotide biosynthesis]]
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[[Category: Protein-ligand complex]]
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[[Category: Transferase]]
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Current revision

Crystal structure of mouse thymidylate synthase

PDB ID 3ihi

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