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3iu1
From Proteopedia
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| - | [[Image:3iu1.png|left|200px]] | ||
| - | + | ==Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA== | |
| - | + | <StructureSection load='3iu1' size='340' side='right'caption='[[3iu1]], [[Resolution|resolution]] 1.42Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3iu1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IU1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IU1 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.42Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MYA:TETRADECANOYL-COA'>MYA</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iu1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iu1 OCA], [https://pdbe.org/3iu1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iu1 RCSB], [https://www.ebi.ac.uk/pdbsum/3iu1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iu1 ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/NMT1_HUMAN NMT1_HUMAN] Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. | |
| - | + | == Evolutionary Conservation == | |
| - | == | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [[3iu1]] is a 2 chain structure with sequence from [ | + | Check<jmol> |
| - | [[ | + | <jmolCheckbox> |
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iu/3iu1_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3iu1 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Arrowsmith | + | [[Category: Large Structures]] |
| - | [[Category: Bochkarev | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Bountra | + | [[Category: Bochkarev A]] |
| - | [[Category: Brand | + | [[Category: Bountra C]] |
| - | [[Category: Cossar | + | [[Category: Brand SY]] |
| - | [[Category: Edwards | + | [[Category: Cossar D]] |
| - | [[Category: Ferguson | + | [[Category: Edwards AM]] |
| - | [[Category: Frearson | + | [[Category: Ferguson MAJ]] |
| - | [[Category: Hui | + | [[Category: Frearson JA]] |
| - | [[Category: Hutchinson | + | [[Category: Hui R]] |
| - | [[Category: Kania | + | [[Category: Hutchinson A]] |
| - | [[Category: Kozieradzki | + | [[Category: Kania A]] |
| - | [[Category: Lin | + | [[Category: Kozieradzki I]] |
| - | [[Category: Qiu | + | [[Category: Lin Y-H]] |
| - | [[Category: Ravichandran | + | [[Category: Qiu W]] |
| - | [[Category: Robinson | + | [[Category: Ravichandran M]] |
| - | + | [[Category: Robinson DA]] | |
| - | [[Category: Schapira | + | [[Category: Schapira M]] |
| - | [[Category: Weigelt | + | [[Category: Weigelt J]] |
| - | [[Category: Wernimont | + | [[Category: Wernimont A]] |
| - | [[Category: Wyatt | + | [[Category: Wyatt PG]] |
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Current revision
Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bochkarev A | Bountra C | Brand SY | Cossar D | Edwards AM | Ferguson MAJ | Frearson JA | Hui R | Hutchinson A | Kania A | Kozieradzki I | Lin Y-H | Qiu W | Ravichandran M | Robinson DA | Schapira M | Weigelt J | Wernimont A | Wyatt PG

