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3kre

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==Crystal structure of phosphoribosylaminoimidazole-succinocarboxamide synthase from Ehrlichia chaffeensis at 1.8A resolution==
==Crystal structure of phosphoribosylaminoimidazole-succinocarboxamide synthase from Ehrlichia chaffeensis at 1.8A resolution==
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<StructureSection load='3kre' size='340' side='right' caption='[[3kre]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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<StructureSection load='3kre' size='340' side='right'caption='[[3kre]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3kre]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ehrlichia_chaffeensis_str._arkansas Ehrlichia chaffeensis str. arkansas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KRE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KRE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3kre]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ehrlichia_chaffeensis_str._Arkansas Ehrlichia chaffeensis str. Arkansas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KRE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KRE FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">purC, ECH_0290 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=205920 Ehrlichia chaffeensis str. Arkansas])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoribosylaminoimidazolesuccinocarboxamide_synthase Phosphoribosylaminoimidazolesuccinocarboxamide synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.6 6.3.2.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kre OCA], [https://pdbe.org/3kre PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kre RCSB], [https://www.ebi.ac.uk/pdbsum/3kre PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kre ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kre OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3kre RCSB], [http://www.ebi.ac.uk/pdbsum/3kre PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PUR7_EHRCR PUR7_EHRCR]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kr/3kre_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kr/3kre_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kre ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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==See Also==
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*[[SAICAR synthetase|SAICAR synthetase]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ehrlichia chaffeensis str. arkansas]]
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[[Category: Ehrlichia chaffeensis str. Arkansas]]
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[[Category: Phosphoribosylaminoimidazolesuccinocarboxamide synthase]]
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[[Category: Large Structures]]
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[[Category: Structural genomic]]
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[[Category: Atp-binding]]
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[[Category: Ehrlichia chaffeensis]]
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[[Category: Emerald biostructure]]
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[[Category: Ligase]]
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[[Category: Niaid]]
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[[Category: Nih]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphoribosylaminoimidazole-succinocarboxamide synthase]]
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[[Category: Purine biosynthesis]]
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[[Category: Sbri]]
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[[Category: Ssgcid]]
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[[Category: Uw]]
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Current revision

Crystal structure of phosphoribosylaminoimidazole-succinocarboxamide synthase from Ehrlichia chaffeensis at 1.8A resolution

PDB ID 3kre

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