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3kuf

From Proteopedia

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{{STRUCTURE_3kuf| PDB=3kuf | SCENE= }}
 
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===The Crystal Structure of the Tudor Domains from FXR1===
 
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==Function==
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==The Crystal Structure of the Tudor Domains from FXR1==
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[[http://www.uniprot.org/uniprot/FXR1_HUMAN FXR1_HUMAN]] RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulate intracellular transport and local translation of certain mRNAs (By similarity).
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<StructureSection load='3kuf' size='340' side='right'caption='[[3kuf]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[3kuf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KUF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KUF FirstGlance]. <br>
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[[3kuf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KUF OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kuf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kuf OCA], [https://pdbe.org/3kuf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kuf RCSB], [https://www.ebi.ac.uk/pdbsum/3kuf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kuf ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FXR1_HUMAN FXR1_HUMAN] RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulate intracellular transport and local translation of certain mRNAs (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ku/3kuf_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kuf ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Adams-Cioaba, M A.]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith,C H.]]
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[[Category: Adams-Cioaba MA]]
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[[Category: Bian,C.]]
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[[Category: Arrowsmith CH]]
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[[Category: Bochkarev,A.]]
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[[Category: Bian C]]
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[[Category: Bountra, C.]]
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[[Category: Bochkarev A]]
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[[Category: Edwards,A M.]]
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[[Category: Bountra C]]
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[[Category: Guo, Y H.]]
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[[Category: Edwards AM]]
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[[Category: Kozieradzki, I.]]
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[[Category: Guo YH]]
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[[Category: Mackenzie, F.]]
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[[Category: Kozieradzki I]]
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[[Category: Min,J.]]
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[[Category: Mackenzie F]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Min J]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt J]]
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[[Category: Protein binding]]
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[[Category: Rna-binding fragile x mental retardation syndrome-related protein 1]]
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[[Category: Sgc]]
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[[Category: Structural genomics consortium]]
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[[Category: Tandem tudor]]
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Current revision

The Crystal Structure of the Tudor Domains from FXR1

PDB ID 3kuf

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OCA

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