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3lg0

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==Structure of Plasmodium falciparum ornithine delta-aminotransferase==
==Structure of Plasmodium falciparum ornithine delta-aminotransferase==
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<StructureSection load='3lg0' size='340' side='right' caption='[[3lg0]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='3lg0' size='340' side='right'caption='[[3lg0]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3lg0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Plafd Plafd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LG0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LG0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3lg0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_CDC/Honduras Plasmodium falciparum CDC/Honduras]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LG0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LG0 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">OAT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5836 PLAFD])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ornithine_aminotransferase Ornithine aminotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.13 2.6.1.13] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lg0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lg0 OCA], [https://pdbe.org/3lg0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lg0 RCSB], [https://www.ebi.ac.uk/pdbsum/3lg0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lg0 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lg0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lg0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lg0 RCSB], [http://www.ebi.ac.uk/pdbsum/3lg0 PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/OAT_PLAFD OAT_PLAFD]] The enzyme has a very narrow substrate specificity and can only catalyze the transamination of alpha-ketoglutarate with ornithine or N-acetylornithine and of glutamate-5-semialdehyde with glutamate and alanine (By similarity).
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[https://www.uniprot.org/uniprot/OAT_PLAF7 OAT_PLAF7] The enzyme has a very narrow substrate specificity and can only catalyze the transamination of alpha-ketoglutarate with ornithine or N-acetylornithine and of glutamate-5-semialdehyde with glutamate and alanine.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lg/3lg0_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lg/3lg0_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lg0 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3lg0" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ornithine aminotransferase]]
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[[Category: Large Structures]]
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[[Category: Plafd]]
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[[Category: Plasmodium falciparum CDC/Honduras]]
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[[Category: Becker, K]]
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[[Category: Becker K]]
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[[Category: Fritz-Wolf, K]]
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[[Category: Fritz-Wolf K]]
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[[Category: Jortzik, E]]
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[[Category: Jortzik E]]
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[[Category: Stumpf, M]]
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[[Category: Stumpf M]]
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[[Category: Activation of plasmodium falciparum ornithine delta-aminotransferase]]
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[[Category: Alpha-ketoglutarate]]
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[[Category: Aminotransferase]]
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[[Category: Delta-aminotransferase]]
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[[Category: Ornithine]]
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[[Category: Plasmodium falciparum]]
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[[Category: Pyridoxal phosphate]]
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[[Category: Pyridoxal-5-phosphate-dependent enzyme]]
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[[Category: Transferase]]
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Current revision

Structure of Plasmodium falciparum ornithine delta-aminotransferase

PDB ID 3lg0

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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