3lhy

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:37, 6 September 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==Crystal structure of the mutant I199A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP==
==Crystal structure of the mutant I199A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP==
-
<StructureSection load='3lhy' size='340' side='right' caption='[[3lhy]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
+
<StructureSection load='3lhy' size='340' side='right'caption='[[3lhy]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3lhy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Metth Metth]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LHY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LHY FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3lhy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus_str._Delta_H Methanothermobacter thermautotrophicus str. Delta H]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LHY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LHY FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMQ:1-(5-PHOSPHO-BETA-D-RIBOFURANOSYL)BARBITURIC+ACID'>BMQ</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3lht|3lht]], [[3lhu|3lhu]], [[3lhv|3lhv]], [[3lhw|3lhw]], [[3lhz|3lhz]], [[3li0|3li0]], [[3li1|3li1]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMQ:1-(5-PHOSPHO-BETA-D-RIBOFURANOSYL)BARBITURIC+ACID'>BMQ</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pyrF, MTH_129 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=187420 METTH])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lhy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lhy OCA], [https://pdbe.org/3lhy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lhy RCSB], [https://www.ebi.ac.uk/pdbsum/3lhy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lhy ProSAT]</span></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotidine-5'-phosphate_decarboxylase Orotidine-5'-phosphate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.23 4.1.1.23] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lhy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lhy OCA], [http://pdbe.org/3lhy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3lhy RCSB], [http://www.ebi.ac.uk/pdbsum/3lhy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3lhy ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/PYRF_METTH PYRF_METTH]] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).[HAMAP-Rule:MF_01200_A]
+
[https://www.uniprot.org/uniprot/PYRF_METTH PYRF_METTH] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).[HAMAP-Rule:MF_01200_A]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 33: Line 31:
==See Also==
==See Also==
-
*[[Uridine 5'-monophosphate synthase|Uridine 5'-monophosphate synthase]]
+
*[[Uridine 5'-monophosphate synthase 3D structures|Uridine 5'-monophosphate synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Metth]]
+
[[Category: Large Structures]]
-
[[Category: Orotidine-5'-phosphate decarboxylase]]
+
[[Category: Methanothermobacter thermautotrophicus str. Delta H]]
-
[[Category: Almo, S C]]
+
[[Category: Almo SC]]
-
[[Category: Fedorov, A A]]
+
[[Category: Fedorov AA]]
-
[[Category: Fedorov, E V]]
+
[[Category: Fedorov EV]]
-
[[Category: Gerlt, J A]]
+
[[Category: Gerlt JA]]
-
[[Category: Wood, B M]]
+
[[Category: Wood BM]]
-
[[Category: 6-hydroxyuridine-5'-phosphate]]
+
-
[[Category: Decarboxylase]]
+
-
[[Category: Lyase]]
+
-
[[Category: Mutant i199a]]
+
-
[[Category: Pyrimidine biosynthesis]]
+

Current revision

Crystal structure of the mutant I199A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP

PDB ID 3lhy

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3lhy"
Personal tools