This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3lix

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:37, 6 September 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='3lix' size='340' side='right'caption='[[3lix]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='3lix' size='340' side='right'caption='[[3lix]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3lix]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Htlv-1 Htlv-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LIX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LIX FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3lix]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_T-cell_leukemia_virus_type_I Human T-cell leukemia virus type I]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LIX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LIX FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=E17:N-{(1S,2S)-1-benzyl-3-[(4R)-5,5-dimethyl-4-{[(1R)-1,2,2-trimethylpropyl]carbamoyl}-1,3-thiazolidin-3-yl]-2-hydroxy-3-oxopropyl}-3-methyl-N~2~-{(2S)-2-[(morpholin-4-ylacetyl)amino]-2-phenylacetyl}-L-valinamide'>E17</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2b7f|2b7f]], [[3liq|3liq]], [[3lin|3lin]], [[3lit|3lit]], [[3liv|3liv]], [[3liy|3liy]]</div></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=E17:N-{(1S,2S)-1-benzyl-3-[(4R)-5,5-dimethyl-4-{[(1R)-1,2,2-trimethylpropyl]carbamoyl}-1,3-thiazolidin-3-yl]-2-hydroxy-3-oxopropyl}-3-methyl-N~2~-{(2S)-2-[(morpholin-4-ylacetyl)amino]-2-phenylacetyl}-L-valinamide'>E17</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">prt ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11908 HTLV-1])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lix FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lix OCA], [https://pdbe.org/3lix PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lix RCSB], [https://www.ebi.ac.uk/pdbsum/3lix PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lix ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lix FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lix OCA], [https://pdbe.org/3lix PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lix RCSB], [https://www.ebi.ac.uk/pdbsum/3lix PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lix ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q82134_9DELA Q82134_9DELA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 35: Line 36:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Htlv-1]]
+
[[Category: Human T-cell leukemia virus type I]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Gustchina, A]]
+
[[Category: Gustchina A]]
-
[[Category: Kiso, Y]]
+
[[Category: Kiso Y]]
-
[[Category: Li, M]]
+
[[Category: Li M]]
-
[[Category: Nguyen, J]]
+
[[Category: Nguyen J]]
-
[[Category: Satoh, T]]
+
[[Category: Satoh T]]
-
[[Category: Wlodawer, A]]
+
[[Category: Wlodawer A]]
-
[[Category: Hydrolase]]
+
-
[[Category: Hydrolase-hydrolase inhibitor complex]]
+

Current revision

crystal structure of htlv protease complexed with the inhibitor KNI-10729

PDB ID 3lix

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3lix"
Personal tools