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3lm0
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3lm0 is ON HOLD Authors: Ugochukwu, E., Soundararajan, M., Rellos, P., Fedorov, O., Phillips, C., Wang, J., Hapka, E., Filippakopoulos, P., Chaikuad...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of human Serine/Threonine Kinase 17B (STK17B)== | |
| + | <StructureSection load='3lm0' size='340' side='right'caption='[[3lm0]], [[Resolution|resolution]] 2.35Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3lm0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LM0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LM0 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EBD:[4-({4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]-5-METHYLPYRIMIDIN-2-YL}AMINO)PHENYL]ACETONITRILE'>EBD</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lm0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lm0 OCA], [https://pdbe.org/3lm0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lm0 RCSB], [https://www.ebi.ac.uk/pdbsum/3lm0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lm0 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ST17B_HUMAN ST17B_HUMAN] Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis.<ref>PMID:9786912</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lm/3lm0_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lm0 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| - | + | *[[Serine/threonine protein kinase 3D structures|Serine/threonine protein kinase 3D structures]] | |
| - | + | == References == | |
| - | + | <references/> | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Arrowsmith CH]] | ||
| + | [[Category: Bountra C]] | ||
| + | [[Category: Chaikuad A]] | ||
| + | [[Category: Edwards A]] | ||
| + | [[Category: Fedorov O]] | ||
| + | [[Category: Filippakopoulos P]] | ||
| + | [[Category: Hapka E]] | ||
| + | [[Category: Knapp S]] | ||
| + | [[Category: Phillips C]] | ||
| + | [[Category: Pike ACW]] | ||
| + | [[Category: Rellos P]] | ||
| + | [[Category: Soundararajan M]] | ||
| + | [[Category: Ugochukwu E]] | ||
| + | [[Category: Wang J]] | ||
| + | [[Category: Weigelt J]] | ||
| + | [[Category: Von Delft F]] | ||
Current revision
Crystal Structure of human Serine/Threonine Kinase 17B (STK17B)
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Chaikuad A | Edwards A | Fedorov O | Filippakopoulos P | Hapka E | Knapp S | Phillips C | Pike ACW | Rellos P | Soundararajan M | Ugochukwu E | Wang J | Weigelt J | Von Delft F
