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3lvv

From Proteopedia

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==BSO-inhibited ScGCL==
==BSO-inhibited ScGCL==
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<StructureSection load='3lvv' size='340' side='right' caption='[[3lvv]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='3lvv' size='340' side='right'caption='[[3lvv]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3lvv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LVV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LVV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3lvv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LVV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LVV FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=LBP:(2S)-2-AMINO-4-(S-BUTYL-N-PHOSPHONOSULFONIMIDOYL)BUTANOIC+ACID'>LBP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ig5|3ig5]], [[3ig8|3ig8]], [[3lvw|3lvw]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=LBP:(2S)-2-AMINO-4-(S-BUTYL-N-PHOSPHONOSULFONIMIDOYL)BUTANOIC+ACID'>LBP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GSH1, J0832, YJL101C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lvv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lvv OCA], [https://pdbe.org/3lvv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lvv RCSB], [https://www.ebi.ac.uk/pdbsum/3lvv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lvv ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamate--cysteine_ligase Glutamate--cysteine ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.2 6.3.2.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lvv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lvv OCA], [http://pdbe.org/3lvv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3lvv RCSB], [http://www.ebi.ac.uk/pdbsum/3lvv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3lvv ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GSH1_YEAST GSH1_YEAST]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lv/3lvv_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lv/3lvv_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 18824]]
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[[Category: Large Structures]]
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[[Category: Glutamate--cysteine ligase]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Barycki, J J]]
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[[Category: Barycki JJ]]
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[[Category: Biterova, E I]]
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[[Category: Biterova EI]]
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[[Category: Atp-binding]]
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[[Category: Atp-grasp]]
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[[Category: Glutathione]]
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[[Category: Glutathione biosynthesis]]
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[[Category: Ligase]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphoprotein]]
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Current revision

BSO-inhibited ScGCL

PDB ID 3lvv

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