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3lx4

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==Stepwise [FeFe]-hydrogenase H-cluster assembly revealed in the structure of HydA(deltaEFG)==
==Stepwise [FeFe]-hydrogenase H-cluster assembly revealed in the structure of HydA(deltaEFG)==
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<StructureSection load='3lx4' size='340' side='right' caption='[[3lx4]], [[Resolution|resolution]] 1.97&Aring;' scene=''>
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<StructureSection load='3lx4' size='340' side='right'caption='[[3lx4]], [[Resolution|resolution]] 1.97&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3lx4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chlre Chlre]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LX4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LX4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3lx4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LX4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LX4 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.97&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CHLREDRAFT_183963, hyd1, hydA, hydA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3055 CHLRE])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferredoxin_hydrogenase Ferredoxin hydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.12.7.2 1.12.7.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lx4 OCA], [https://pdbe.org/3lx4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lx4 RCSB], [https://www.ebi.ac.uk/pdbsum/3lx4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lx4 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lx4 OCA], [http://pdbe.org/3lx4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3lx4 RCSB], [http://www.ebi.ac.uk/pdbsum/3lx4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3lx4 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9FYU1_CHLRE Q9FYU1_CHLRE]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lx/3lx4_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lx/3lx4_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Chlre]]
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[[Category: Chlamydomonas reinhardtii]]
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[[Category: Ferredoxin hydrogenase]]
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[[Category: Large Structures]]
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[[Category: Boyd, E S]]
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[[Category: Boyd ES]]
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[[Category: Broderick, J B]]
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[[Category: Broderick JB]]
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[[Category: Endrizzi, J A]]
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[[Category: Endrizzi JA]]
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[[Category: Lange, R K]]
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[[Category: Lange RK]]
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[[Category: Mulder, D W]]
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[[Category: Mulder DW]]
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[[Category: Peters, J W]]
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[[Category: Peters JW]]
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[[Category: Sarma, R]]
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[[Category: Sarma R]]
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[[Category: Biosynthesis]]
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[[Category: Evolution]]
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[[Category: H-cluster]]
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[[Category: Hyda]]
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[[Category: Hydrogen]]
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[[Category: Hydrogenase]]
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[[Category: Insertion]]
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[[Category: Intermediate]]
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[[Category: Iron-sulfur cluster]]
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[[Category: Maturation]]
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[[Category: Oxidoreductase]]
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Current revision

Stepwise [FeFe]-hydrogenase H-cluster assembly revealed in the structure of HydA(deltaEFG)

PDB ID 3lx4

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