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3mhu

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Current revision (08:53, 6 September 2023) (edit) (undo)
 
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<StructureSection load='3mhu' size='340' side='right'caption='[[3mhu]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='3mhu' size='340' side='right'caption='[[3mhu]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3mhu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_major_mhom/il/81/friedlin Leishmania major mhom/il/81/friedlin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MHU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MHU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3mhu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_major_strain_Friedlin Leishmania major strain Friedlin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MHU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MHU FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EJZ:5-NITRO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC+ACID'>EJZ</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3gye|3gye]], [[3c3n|3c3n]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EJZ:5-NITRO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC+ACID'>EJZ</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LmjF16.0530 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=347515 Leishmania major MHOM/IL/81/Friedlin])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Dihydroorotate_oxidase_(fumarate) Dihydroorotate oxidase (fumarate)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.98.1 1.3.98.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mhu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mhu OCA], [https://pdbe.org/3mhu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mhu RCSB], [https://www.ebi.ac.uk/pdbsum/3mhu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mhu ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mhu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mhu OCA], [https://pdbe.org/3mhu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mhu RCSB], [https://www.ebi.ac.uk/pdbsum/3mhu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mhu ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q4QEW7_LEIMA Q4QEW7_LEIMA]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Leishmania major mhom/il/81/friedlin]]
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[[Category: Leishmania major strain Friedlin]]
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[[Category: Cheleski, J]]
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[[Category: Cheleski J]]
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[[Category: Montanari, C A]]
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[[Category: Montanari CA]]
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[[Category: Nonato, M C]]
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[[Category: Nonato MC]]
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[[Category: Pinheiro, M P]]
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[[Category: Pinheiro MP]]
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[[Category: Rocha, J R]]
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[[Category: Rocha JR]]
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[[Category: Dihydroorotate dehydrogenase]]
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[[Category: Oxidoreductase]]
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[[Category: Pyrd]]
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Current revision

Crystal structure of dihydroorotate dehydrogenase from Leishmania major in complex with 5-Nitroorotic acid

PDB ID 3mhu

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