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3mpj

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==Structure of the glutaryl-coenzyme A dehydrogenase==
==Structure of the glutaryl-coenzyme A dehydrogenase==
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<StructureSection load='3mpj' size='340' side='right' caption='[[3mpj]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='3mpj' size='340' side='right'caption='[[3mpj]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3mpj]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Desulfococcus_multivorans Desulfococcus multivorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MPJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MPJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3mpj]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Desulfococcus_multivorans Desulfococcus multivorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MPJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MPJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3mpi|3mpi]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">acd, gi228015642 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=897 Desulfococcus multivorans])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mpj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mpj OCA], [https://pdbe.org/3mpj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mpj RCSB], [https://www.ebi.ac.uk/pdbsum/3mpj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mpj ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutaryl-CoA_dehydrogenase Glutaryl-CoA dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.99.7 1.3.99.7] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mpj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mpj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mpj RCSB], [http://www.ebi.ac.uk/pdbsum/3mpj PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/C3UVB0_9DELT C3UVB0_9DELT]] Catalyzes the dehydrogenation of Glutaryl-CoA to glutaconyl-CoA.<ref>PMID:19395484</ref>
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[https://www.uniprot.org/uniprot/ACD_DESML ACD_DESML] Catalyzes the dehydrogenation of Glutaryl-CoA to glutaconyl-CoA.<ref>PMID:19395484</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mp/3mpj_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mp/3mpj_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3mpj ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3mpj" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Acyl-CoA dehydrogenase 3D structures|Acyl-CoA dehydrogenase 3D structures]]
*[[Glutaryl-CoA dehydrogenase|Glutaryl-CoA dehydrogenase]]
*[[Glutaryl-CoA dehydrogenase|Glutaryl-CoA dehydrogenase]]
== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Desulfococcus multivorans]]
[[Category: Desulfococcus multivorans]]
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[[Category: Glutaryl-CoA dehydrogenase]]
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[[Category: Large Structures]]
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[[Category: Boll, M]]
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[[Category: Boll M]]
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[[Category: Ermler, U]]
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[[Category: Ermler U]]
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[[Category: Warkentin, E]]
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[[Category: Warkentin E]]
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[[Category: Wischgoll, S]]
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[[Category: Wischgoll S]]
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[[Category: Alpha-beta fold]]
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[[Category: Oxidoreductase]]
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Current revision

Structure of the glutaryl-coenzyme A dehydrogenase

PDB ID 3mpj

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