This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3ncg

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:12, 6 September 2023) (edit) (undo)
 
Line 1: Line 1:
==Activated Calcium-Dependent Protein Kinase 1 from Cryptosporidium parvum (CpCDPK1) in complex with bumped kinase inhibitor NM-PP1==
==Activated Calcium-Dependent Protein Kinase 1 from Cryptosporidium parvum (CpCDPK1) in complex with bumped kinase inhibitor NM-PP1==
-
<StructureSection load='3ncg' size='340' side='right' caption='[[3ncg]], [[Resolution|resolution]] 2.49&Aring;' scene=''>
+
<StructureSection load='3ncg' size='340' side='right'caption='[[3ncg]], [[Resolution|resolution]] 2.49&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3ncg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Crypi Crypi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NCG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NCG FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3ncg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NCG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NCG FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BK1:1-(1-METHYLETHYL)-3-(NAPHTHALEN-1-YLMETHYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE'>BK1</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.49&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3i79|3i79]], [[3i7b|3i7b]], [[3i7c|3i7c]], [[3n51|3n51]], [[3mwu|3mwu]], [[3igo|3igo]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BK1:1-(1-METHYLETHYL)-3-(NAPHTHALEN-1-YLMETHYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE'>BK1</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CDPK1, cgd3_920 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353152 CRYPI])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ncg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ncg OCA], [https://pdbe.org/3ncg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ncg RCSB], [https://www.ebi.ac.uk/pdbsum/3ncg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ncg ProSAT]</span></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calcium/calmodulin-dependent_protein_kinase Calcium/calmodulin-dependent protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.17 2.7.11.17] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ncg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ncg OCA], [http://pdbe.org/3ncg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ncg RCSB], [http://www.ebi.ac.uk/pdbsum/3ncg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ncg ProSAT]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/A3FQ16_CRYPI A3FQ16_CRYPI]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nc/3ncg_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nc/3ncg_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
Line 29: Line 29:
</div>
</div>
<div class="pdbe-citations 3ncg" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3ncg" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Calcium-dependent protein kinase|Calcium-dependent protein kinase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Calcium/calmodulin-dependent protein kinase]]
+
[[Category: Cryptosporidium parvum Iowa II]]
-
[[Category: Crypi]]
+
[[Category: Large Structures]]
-
[[Category: Larson, E T]]
+
[[Category: Larson ET]]
-
[[Category: Structural genomic]]
+
[[Category: Merritt EA]]
-
[[Category: Merritt, E A]]
+
-
[[Category: Atp-binding]]
+
-
[[Category: Bumped kinase inhibitor]]
+
-
[[Category: Calcium-binding]]
+
-
[[Category: Calmodulin]]
+
-
[[Category: Msgpp]]
+
-
[[Category: Serine/threonine protein kinase]]
+
-
[[Category: Transferase]]
+
-
[[Category: Transferase-transferase inhibitor complex]]
+

Current revision

Activated Calcium-Dependent Protein Kinase 1 from Cryptosporidium parvum (CpCDPK1) in complex with bumped kinase inhibitor NM-PP1

PDB ID 3ncg

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3ncg"
Personal tools