This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3nj2
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3nj2 is ON HOLD Authors: Robinson, H., Ralston, C.Y., Addlagatta, A., Buchko, G.W. Description: Crystal structure of cce_0566 from the cyanobacteri...) |
|||
| (8 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of cce_0566 from the cyanobacterium Cyanothece 51142, a protein associated with nitrogen fixation from the DUF269 family== | |
| + | <StructureSection load='3nj2' size='340' side='right'caption='[[3nj2]], [[Resolution|resolution]] 1.59Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3nj2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Crocosphaera_subtropica_ATCC_51142 Crocosphaera subtropica ATCC 51142]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NJ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NJ2 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.59Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nj2 OCA], [https://pdbe.org/3nj2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nj2 RCSB], [https://www.ebi.ac.uk/pdbsum/3nj2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nj2 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/B1WPD5_CROS5 B1WPD5_CROS5] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nj/3nj2_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nj2 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The crystal structure for cce_0566 (171 aa, 19.4kDa), a DUF269 annotated protein from the diazotrophic cyanobacterium Cyanothece sp. ATCC 51142, was determined to 1.60A resolution. Cce_0566 is a homodimer with each molecule composed of eight alpha-helices folded on one side of a three strand anti-parallel beta-sheet. Hydrophobic interactions between the side chains of largely conserved residues on the surface of each beta-sheet hold the dimer together. The fold observed for cce_0566 may be unique to proteins in the DUF269 family, hence, the protein may also have a function unique to nitrogen fixation. A solvent accessible cleft containing conserved charged residues near the dimer interface could represent the active site or ligand-binding surface for the protein's biological function. STRUCTURED SUMMARY OF PROTEIN INTERACTIONS: DUF269 and DUF269bind by x-ray crystallography (View interaction). | ||
| - | + | Crystal structure of cce_0566 from Cyanothece 51142, a protein associated with nitrogen fixation in the DUF269 family.,Buchko GW, Robinson H FEBS Lett. 2012 Feb 17;586(4):350-5. Epub 2012 Jan 28. PMID:22289180<ref>PMID:22289180</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | <div class="pdbe-citations 3nj2" style="background-color:#fffaf0;"></div> | |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Crocosphaera subtropica ATCC 51142]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Addlagatta A]] | ||
| + | [[Category: Buchko GW]] | ||
| + | [[Category: Ralston CY]] | ||
| + | [[Category: Robinson H]] | ||
Current revision
Crystal structure of cce_0566 from the cyanobacterium Cyanothece 51142, a protein associated with nitrogen fixation from the DUF269 family
| |||||||||||
