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3nk3

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==Crystal structure of full-length sperm receptor ZP3 at 2.6 A resolution==
==Crystal structure of full-length sperm receptor ZP3 at 2.6 A resolution==
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<StructureSection load='3nk3' size='340' side='right' caption='[[3nk3]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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<StructureSection load='3nk3' size='340' side='right'caption='[[3nk3]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3nk3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NK3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NK3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3nk3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NK3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NK3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3d4c|3d4c]], [[3d4g|3d4g]], [[3ef7|3ef7]], [[3nk4|3nk4]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=PRD_900084:Thomsen-Friedenreich+antigen'>PRD_900084</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nk3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nk3 RCSB], [http://www.ebi.ac.uk/pdbsum/3nk3 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nk3 OCA], [https://pdbe.org/3nk3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nk3 RCSB], [https://www.ebi.ac.uk/pdbsum/3nk3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nk3 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ZP3_CHICK ZP3_CHICK] Component of the zona pellucida, which mediates species-specific sperm binding. Directly binds to sperm. Important for egg fertilization.<ref>PMID:15115720</ref> <ref>PMID:20970175</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3nk3" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
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[[Category: Jovine, L]]
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[[Category: Large Structures]]
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[[Category: Monne , M]]
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[[Category: Jovine L]]
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[[Category: Biodiversity]]
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[[Category: Monne M]]
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[[Category: Cell adhesion]]
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[[Category: Core-1]]
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[[Category: Egg coat]]
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[[Category: Egg-sperm interaction]]
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[[Category: Ehp]]
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[[Category: External hydrophobic patch]]
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[[Category: Extracellular matrix]]
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[[Category: Fertilization]]
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[[Category: Glycoprotein]]
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[[Category: Ihp]]
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[[Category: Immunoglobulin-like fold]]
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[[Category: Infertility]]
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[[Category: Internal hydrophobic patch]]
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[[Category: O-linked carbohydrate]]
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[[Category: Oocyte]]
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[[Category: Receptor]]
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[[Category: Secreted]]
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[[Category: Speciation]]
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[[Category: Species-specific gamete recognition]]
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[[Category: Sperm-combining site]]
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[[Category: T-antigen]]
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[[Category: Transmembrane]]
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[[Category: Vitelline envelope]]
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[[Category: Zona pellucida]]
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[[Category: Zp domain]]
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[[Category: Zp module]]
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Current revision

Crystal structure of full-length sperm receptor ZP3 at 2.6 A resolution

PDB ID 3nk3

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