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3nyv

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{{STRUCTURE_3nyv| PDB=3nyv | SCENE= }}
 
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===Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with non-specific inhibitor WHI-P180===
 
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==About this Structure==
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==Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with non-specific inhibitor WHI-P180==
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[[3nyv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NYV OCA].
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<StructureSection load='3nyv' size='340' side='right'caption='[[3nyv]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
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[[Category: Calcium/calmodulin-dependent protein kinase]]
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3nyv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NYV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NYV FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.88&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTQ:4-[3-HYDROXYANILINO]-6,7-DIMETHOXYQUINAZOLINE'>DTQ</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nyv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nyv OCA], [https://pdbe.org/3nyv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nyv RCSB], [https://www.ebi.ac.uk/pdbsum/3nyv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nyv ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9BJF5_TOXGO Q9BJF5_TOXGO]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ny/3nyv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nyv ConSurf].
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<div style="clear:both"></div>
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==See Also==
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*[[Calcium-dependent protein kinase|Calcium-dependent protein kinase]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Toxoplasma gondii]]
[[Category: Toxoplasma gondii]]
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[[Category: Larson, E T.]]
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[[Category: Larson ET]]
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[[Category: MSGPP, Medical Structural Genomics of Pathogenic Protozoa.]]
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[[Category: Merritt EA]]
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[[Category: Merritt, E A.]]
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[[Category: Atp-binding]]
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[[Category: Bumped kinase inhibitor]]
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[[Category: Calcium-binding]]
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[[Category: Calmodulin]]
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[[Category: Ef hand]]
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[[Category: Medical structural genomics of pathogenic protozoa]]
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[[Category: Msgpp]]
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[[Category: Serine/threonine protein kinase]]
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[[Category: Structural genomic]]
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[[Category: Transferase]]
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[[Category: Transferase-transferase inhibitor complex]]
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Current revision

Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with non-specific inhibitor WHI-P180

PDB ID 3nyv

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