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3o2u

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==S. cerevisiae Ubc12==
==S. cerevisiae Ubc12==
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<StructureSection load='3o2u' size='340' side='right' caption='[[3o2u]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='3o2u' size='340' side='right'caption='[[3o2u]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3o2u]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O2U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O2U FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3o2u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O2U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3O2U FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.003&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3o2p|3o2p]], [[3o6b|3o6b]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">UBC12, YLR306W, L2142.3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3o2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o2u OCA], [https://pdbe.org/3o2u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3o2u RCSB], [https://www.ebi.ac.uk/pdbsum/3o2u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3o2u ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o2u OCA], [http://pdbe.org/3o2u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3o2u RCSB], [http://www.ebi.ac.uk/pdbsum/3o2u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3o2u ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/UBC12_YEAST UBC12_YEAST]] Accepts the ubiquitin-like protein NEDD8/RUB1 from the UBA3-ULA1 E1 complex and catalyzes its covalent attachment to other proteins. The major substrate is CDC53/Cullin.<ref>PMID:9545234</ref>
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[https://www.uniprot.org/uniprot/UBC12_YEAST UBC12_YEAST] Accepts the ubiquitin-like protein NEDD8/RUB1 from the UBA3-ULA1 E1 complex and catalyzes its covalent attachment to other proteins. The major substrate is CDC53/Cullin.<ref>PMID:9545234</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o2/3o2u_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o2/3o2u_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[Ubiquitin conjugating enzyme|Ubiquitin conjugating enzyme]]
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*[[3D structures of ubiquitin conjugating enzyme|3D structures of ubiquitin conjugating enzyme]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 18824]]
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[[Category: Large Structures]]
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[[Category: Duda, D M]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Grace, C R.R]]
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[[Category: Duda DM]]
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[[Category: Kriwacki, R W]]
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[[Category: Grace CRR]]
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[[Category: Kurz, T]]
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[[Category: Kriwacki RW]]
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[[Category: Monda, J K]]
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[[Category: Kurz T]]
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[[Category: Schulman, B A]]
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[[Category: Monda JK]]
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[[Category: Scott, D C]]
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[[Category: Schulman BA]]
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[[Category: E2 conjugase]]
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[[Category: Scott DC]]
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[[Category: Ligase]]
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Current revision

S. cerevisiae Ubc12

PDB ID 3o2u

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