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3ob9

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{{Seed}}
 
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[[Image:3ob9.jpg|left|200px]]
 
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==Structure of the human MSL3 chromo-barrel domain at 2.5 Angstrom resolution==
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The line below this paragraph, containing "STRUCTURE_3ob9", creates the "Structure Box" on the page.
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<StructureSection load='3ob9' size='340' side='right'caption='[[3ob9]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3ob9]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OB9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OB9 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NHE:2-[N-CYCLOHEXYLAMINO]ETHANE+SULFONIC+ACID'>NHE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_3ob9| PDB=3ob9 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ob9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ob9 OCA], [https://pdbe.org/3ob9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ob9 RCSB], [https://www.ebi.ac.uk/pdbsum/3ob9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ob9 ProSAT]</span></td></tr>
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</table>
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===Structure of the human MSL3 chromo-barrel domain at 2.5 Angstrom resolution===
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== Function ==
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[https://www.uniprot.org/uniprot/MS3L1_HUMAN MS3L1_HUMAN] May be involved in chromatin remodeling and transcriptional regulation. May have a role in X inactivation. Component of the MSL complex which is responsible for the majority of histone H4 acetylation at 'Lys-16' which is implicated in the formation of higher-order chromatin structure. Specifically recognizes histone H4 monomethylated at 'Lys-20' (H4K20Me1) in a DNA-dependent manner and is proposed to be involved in chromosomal targeting of the MSL complex.<ref>PMID:16227571</ref> <ref>PMID:20018852</ref> <ref>PMID:20657587</ref> <ref>PMID:20943666</ref>
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== References ==
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==About this Structure==
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<references/>
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3OB9 is a 5 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OB9 OCA].
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Ferhatoglu, Y.]]
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[[Category: Large Structures]]
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[[Category: Moore, S A.]]
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[[Category: Ferhatoglu Y]]
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[[Category: Chromo]]
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[[Category: Moore SA]]
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[[Category: Chromo-barrel]]
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[[Category: Chromodomain]]
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[[Category: Histone h4k20me1]]
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[[Category: Histone tail]]
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[[Category: Methyllysine binding]]
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[[Category: Nucleosome recognition]]
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[[Category: Nucleus]]
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[[Category: Transcription regulator]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 13 10:50:20 2010''
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Current revision

Structure of the human MSL3 chromo-barrel domain at 2.5 Angstrom resolution

PDB ID 3ob9

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