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3oo0

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Current revision (09:42, 6 September 2023) (edit) (undo)
 
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<StructureSection load='3oo0' size='340' side='right'caption='[[3oo0]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
<StructureSection load='3oo0' size='340' side='right'caption='[[3oo0]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3oo0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OO0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OO0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3oo0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OO0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OO0 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1fqw|1fqw]], [[3oo1|3oo1]], [[3chy|3chy]], [[3myy|3myy]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cheY ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3oo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3oo0 OCA], [https://pdbe.org/3oo0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3oo0 RCSB], [https://www.ebi.ac.uk/pdbsum/3oo0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3oo0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3oo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3oo0 OCA], [https://pdbe.org/3oo0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3oo0 RCSB], [https://www.ebi.ac.uk/pdbsum/3oo0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3oo0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/CHEY_ECOLI CHEY_ECOLI]] Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation. Overexpression of CheY in association with MotA and MotB improves motility of a ycgR disruption, suggesting there is an interaction (direct or indirect) between the c-di-GMP-binding flagellar brake protein and the flagellar stator.<ref>PMID:20346719</ref>
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[https://www.uniprot.org/uniprot/CHEY_ECOLI CHEY_ECOLI] Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation. Overexpression of CheY in association with MotA and MotB improves motility of a ycgR disruption, suggesting there is an interaction (direct or indirect) between the c-di-GMP-binding flagellar brake protein and the flagellar stator.<ref>PMID:20346719</ref>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ecoli]]
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[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bourret, R B]]
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[[Category: Bourret RB]]
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[[Category: Collins, E J]]
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[[Category: Collins EJ]]
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[[Category: Guanga, G P]]
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[[Category: Guanga GP]]
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[[Category: Immormino, R M]]
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[[Category: Immormino RM]]
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[[Category: Miller, P J]]
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[[Category: Miller PJ]]
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[[Category: Pazy, Y]]
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[[Category: Pazy Y]]
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[[Category: Silversmith, R E]]
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[[Category: Silversmith RE]]
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[[Category: Alpha-beta repeat]]
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[[Category: Chea cheb chex chez]]
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[[Category: Chemotaxis]]
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[[Category: Phosphorylation]]
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[[Category: Response regulator]]
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[[Category: Signaling protein]]
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[[Category: Two-component signaling]]
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Current revision

Structure of apo CheY A113P

PDB ID 3oo0

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