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3p93

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Current revision (09:50, 6 September 2023) (edit) (undo)
 
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<StructureSection load='3p93' size='340' side='right'caption='[[3p93]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='3p93' size='340' side='right'caption='[[3p93]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3p93]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_baa-138 Atcc baa-138]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P93 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P93 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3p93]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Chromohalobacter_salexigens Chromohalobacter salexigens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P93 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P93 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CS2:D-MANNONIC+ACID'>CS2</scene>, <scene name='pdbligand=KDG:2-KETO-3-DEOXYGLUCONATE'>KDG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3ow1|3ow1]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CS2:D-MANNONIC+ACID'>CS2</scene>, <scene name='pdbligand=KDG:2-KETO-3-DEOXYGLUCONATE'>KDG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Csal_2974 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158080 ATCC BAA-138])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p93 OCA], [https://pdbe.org/3p93 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p93 RCSB], [https://www.ebi.ac.uk/pdbsum/3p93 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p93 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p93 OCA], [https://pdbe.org/3p93 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p93 RCSB], [https://www.ebi.ac.uk/pdbsum/3p93 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p93 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DMGD_CHRSD DMGD_CHRSD] Has low dehydratase activity with D-mannonate and D-gluconate, suggesting that these are not physiological substrates and that it has no significant role in the in vivo degradation of these compounds. Has no detectable activity with a panel of 70 other acid sugars (in vitro).<ref>PMID:24697546</ref>
==See Also==
==See Also==
*[[Mandelate racemase/muconate lactonizing enzyme 3D structures|Mandelate racemase/muconate lactonizing enzyme 3D structures]]
*[[Mandelate racemase/muconate lactonizing enzyme 3D structures|Mandelate racemase/muconate lactonizing enzyme 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc baa-138]]
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[[Category: Chromohalobacter salexigens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Almo, S C]]
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[[Category: Almo SC]]
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[[Category: Fedorov, A A]]
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[[Category: Fedorov AA]]
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[[Category: Fedorov, E V]]
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[[Category: Fedorov EV]]
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[[Category: Gerlt, J A]]
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[[Category: Gerlt JA]]
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[[Category: Wichelecki, D]]
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[[Category: Wichelecki D]]
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[[Category: D-gluconate]]
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[[Category: D-mannonate]]
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[[Category: Enolase fold]]
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[[Category: Enolase superfamily]]
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[[Category: Isomerase]]
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[[Category: Multifunctional enzyme]]
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Current revision

Crystal structure of D-mannonate dehydratase from Chromohalobacter Salexigens complexed with MG,D-Mannonate and 2-keto-3-deoxy-D-Gluconate

PDB ID 3p93

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