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3pg4
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The crystal structure of New Delhi Metallo-beta lactamase (NDM-1)== |
| + | <StructureSection load='3pg4' size='340' side='right'caption='[[3pg4]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3pg4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PG4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PG4 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pg4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pg4 OCA], [https://pdbe.org/3pg4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pg4 RCSB], [https://www.ebi.ac.uk/pdbsum/3pg4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pg4 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin. | ||
| - | + | ==See Also== | |
| - | + | *[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Klebsiella pneumoniae]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chang HJ]] | ||
| + | [[Category: Cho YS]] | ||
| + | [[Category: Kim HT]] | ||
Current revision
The crystal structure of New Delhi Metallo-beta lactamase (NDM-1)
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