This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5j1u

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:42, 6 September 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with N-(furan-3-ylmethyl)pyrrolidine-1-carboxamide at 1.80A resolution==
==Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with N-(furan-3-ylmethyl)pyrrolidine-1-carboxamide at 1.80A resolution==
-
<StructureSection load='5j1u' size='340' side='right' caption='[[5j1u]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
+
<StructureSection load='5j1u' size='340' side='right'caption='[[5j1u]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5j1u]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J1U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5J1U FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5j1u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J1U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5J1U FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=P93:N-[(FURAN-3-YL)METHYL]PYRROLIDINE-1-CARBOXAMIDE'>P93</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5j1u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j1u OCA], [http://pdbe.org/5j1u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5j1u RCSB], [http://www.ebi.ac.uk/pdbsum/5j1u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5j1u ProSAT]</span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P93:N-[(FURAN-3-YL)METHYL]PYRROLIDINE-1-CARBOXAMIDE'>P93</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5j1u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j1u OCA], [https://pdbe.org/5j1u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5j1u RCSB], [https://www.ebi.ac.uk/pdbsum/5j1u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5j1u ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 16: Line 19:
</div>
</div>
<div class="pdbe-citations 5j1u" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5j1u" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Abell, C]]
+
[[Category: Large Structures]]
-
[[Category: Blaszczyk, M]]
+
[[Category: Mycobacterium tuberculosis]]
-
[[Category: Blundell, T L]]
+
[[Category: Abell C]]
-
[[Category: Nikiforov, P O]]
+
[[Category: Blaszczyk M]]
-
[[Category: Surade, S]]
+
[[Category: Blundell TL]]
-
[[Category: Boosting effect]]
+
[[Category: Nikiforov PO]]
-
[[Category: Ethr]]
+
[[Category: Surade S]]
-
[[Category: Represor]]
+
-
[[Category: Transcription]]
+

Current revision

Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with N-(furan-3-ylmethyl)pyrrolidine-1-carboxamide at 1.80A resolution

PDB ID 5j1u

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5j1u"
Personal tools