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5jen

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Current revision (11:01, 6 September 2023) (edit) (undo)
 
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<StructureSection load='5jen' size='340' side='right'caption='[[5jen]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='5jen' size='340' side='right'caption='[[5jen]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5jen]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacsu Bacsu] and [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JEN OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5JEN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5jen]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168] and [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JEN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JEN FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rsiV, yrhM, BSU27130 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224308 BACSU])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jen OCA], [https://pdbe.org/5jen PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jen RCSB], [https://www.ebi.ac.uk/pdbsum/5jen PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jen ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5jen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jen OCA], [http://pdbe.org/5jen PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jen RCSB], [http://www.ebi.ac.uk/pdbsum/5jen PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jen ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RSIV_BACSU RSIV_BACSU]] Anti-sigma factor for SigV. Negatively regulates SigV activity through direct interaction.<ref>PMID:16274938</ref> [[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
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[https://www.uniprot.org/uniprot/RSIV_BACSU RSIV_BACSU] Anti-sigma factor for SigV. Negatively regulates SigV activity through direct interaction.<ref>PMID:16274938</ref>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacsu]]
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[[Category: Bacillus subtilis subsp. subtilis str. 168]]
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lysozyme]]
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[[Category: Ellermeir CD]]
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[[Category: Ellermeir, C D]]
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[[Category: Gakhar L]]
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[[Category: Gakhar, L]]
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[[Category: Williams KB]]
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[[Category: Williams, K B]]
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[[Category: Anti-sigma factor]]
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[[Category: Hydrolase-hydrolase receptor complex]]
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[[Category: Inhibitor]]
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[[Category: Receptor]]
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Current revision

Crystal structure of the anti-sigma factor RsiV bound to lysozyme

PDB ID 5jen

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