This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7fpp
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7fpp is ON HOLD Authors: Greisman, J.B., Dalton, K.M., Brookner, D.E., Hekstra, D.R. Description: DHFR:NADP+:FOL complex at 280 K (crystal 5) [[Cat...) |
|||
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==DHFR:NADP+:FOL complex at 280 K (crystal 5)== | |
| - | + | <StructureSection load='7fpp' size='340' side='right'caption='[[7fpp]], [[Resolution|resolution]] 1.03Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7fpp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FPP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FPP FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.03Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=FOL:FOLIC+ACID'>FOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fpp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fpp OCA], [https://pdbe.org/7fpp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fpp RCSB], [https://www.ebi.ac.uk/pdbsum/7fpp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fpp ProSAT]</span></td></tr> |
| - | [[Category: Dalton | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/DYR_ECOLI DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli K-12]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Brookner DE]] | ||
| + | [[Category: Dalton KM]] | ||
| + | [[Category: Greisman JB]] | ||
| + | [[Category: Hekstra DR]] | ||
Current revision
DHFR:NADP+:FOL complex at 280 K (crystal 5)
| |||||||||||
