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7fqc

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Current revision (14:34, 20 September 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 7fqc is ON HOLD until Paper Publication
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==DHFR:NADP+:FOL complex (crystal 2, pass 1, 295 K)==
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<StructureSection load='7fqc' size='340' side='right'caption='[[7fqc]], [[Resolution|resolution]] 1.18&Aring;' scene=''>
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Authors: Greisman, J.B., Dalton, K.M., Brookner, D.E., Hekstra, D.R.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7fqc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FQC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FQC FirstGlance]. <br>
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Description: DHFR:NADP+:FOL complex (crystal 2, pass 1, 295 K)
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.18&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=FOL:FOLIC+ACID'>FOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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[[Category: Hekstra, D.R]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fqc OCA], [https://pdbe.org/7fqc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fqc RCSB], [https://www.ebi.ac.uk/pdbsum/7fqc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fqc ProSAT]</span></td></tr>
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[[Category: Brookner, D.E]]
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</table>
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[[Category: Greisman, J.B]]
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== Function ==
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[[Category: Dalton, K.M]]
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[https://www.uniprot.org/uniprot/DYR_ECOLI DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
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__TOC__
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</StructureSection>
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[[Category: Escherichia coli K-12]]
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[[Category: Large Structures]]
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[[Category: Brookner DE]]
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[[Category: Dalton KM]]
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[[Category: Greisman JB]]
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[[Category: Hekstra DR]]

Current revision

DHFR:NADP+:FOL complex (crystal 2, pass 1, 295 K)

PDB ID 7fqc

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