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4hj0

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==Crystal structure of the human GIPr ECD in complex with Gipg013 Fab at 3-A resolution==
==Crystal structure of the human GIPr ECD in complex with Gipg013 Fab at 3-A resolution==
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<StructureSection load='4hj0' size='340' side='right' caption='[[4hj0]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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<StructureSection load='4hj0' size='340' side='right'caption='[[4hj0]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4hj0]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HJ0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HJ0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4hj0]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HJ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HJ0 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GIPR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hj0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hj0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hj0 RCSB], [http://www.ebi.ac.uk/pdbsum/4hj0 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hj0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hj0 OCA], [https://pdbe.org/4hj0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hj0 RCSB], [https://www.ebi.ac.uk/pdbsum/4hj0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hj0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GIPR_HUMAN GIPR_HUMAN]] This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
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[https://www.uniprot.org/uniprot/GIPR_HUMAN GIPR_HUMAN] This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4hj0" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Monoclonal Antibody|Monoclonal Antibody]]
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*[[Antibody 3D structures|Antibody 3D structures]]
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*[[Glucose-dependent Insulinotropic Polypeptide Receptor|Glucose-dependent Insulinotropic Polypeptide Receptor]]
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*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
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*[[3D structures of human antibody|3D structures of human antibody]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Gruetter, M G]]
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[[Category: Large Structures]]
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[[Category: Jackson, R H]]
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[[Category: Gruetter MG]]
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[[Category: Madhurantakam, C]]
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[[Category: Jackson RH]]
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[[Category: Ravn, P]]
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[[Category: Madhurantakam C]]
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[[Category: Glucagon receptor sub-family recognition fold]]
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[[Category: Ravn P]]
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[[Category: Immune system]]
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Current revision

Crystal structure of the human GIPr ECD in complex with Gipg013 Fab at 3-A resolution

PDB ID 4hj0

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