This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4i9t

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:18, 20 September 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Structure of the H258Y mutant of the phosphatidylinositol-specific phospholipase C from Staphylococcus aureus==
==Structure of the H258Y mutant of the phosphatidylinositol-specific phospholipase C from Staphylococcus aureus==
-
<StructureSection load='4i9t' size='340' side='right' caption='[[4i9t]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
+
<StructureSection load='4i9t' size='340' side='right'caption='[[4i9t]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4i9t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_str._newman Staphylococcus aureus subsp. aureus str. newman]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I9T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4I9T FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4i9t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_str._Newman Staphylococcus aureus subsp. aureus str. Newman]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I9T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I9T FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=INS:1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE'>INS</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3v1h|3v1h]], [[4i9j|4i9j]], [[4i9m|4i9m]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=INS:1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE'>INS</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">plc, NWMN_0041 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=426430 Staphylococcus aureus subsp. aureus str. Newman])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i9t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i9t OCA], [https://pdbe.org/4i9t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i9t RCSB], [https://www.ebi.ac.uk/pdbsum/4i9t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i9t ProSAT]</span></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphatidylinositol_diacylglycerol-lyase Phosphatidylinositol diacylglycerol-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.13 4.6.1.13] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i9t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i9t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4i9t RCSB], [http://www.ebi.ac.uk/pdbsum/4i9t PDBsum]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/PLC_STAAE PLC_STAAE]] Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates. Potential virulence factor.
+
[https://www.uniprot.org/uniprot/PLC_STAAE PLC_STAAE] Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates. Potential virulence factor.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 19: Line 18:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 4i9t" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
-
*[[Phosphatidylinositol-specific phospholipase C|Phosphatidylinositol-specific phospholipase C]]
+
*[[Phospholipase C|Phospholipase C]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Phosphatidylinositol diacylglycerol-lyase]]
+
[[Category: Large Structures]]
-
[[Category: Staphylococcus aureus subsp. aureus str. newman]]
+
[[Category: Staphylococcus aureus subsp. aureus str. Newman]]
-
[[Category: Cheng, J]]
+
[[Category: Cheng J]]
-
[[Category: Gershenson, A]]
+
[[Category: Gershenson A]]
-
[[Category: Goldstein, R I]]
+
[[Category: Goldstein RI]]
-
[[Category: Roberts, M F]]
+
[[Category: Roberts MF]]
-
[[Category: Stec, B]]
+
[[Category: Stec B]]
-
[[Category: Hydrolase]]
+
-
[[Category: Lyase]]
+
-
[[Category: Phospholipase]]
+
-
[[Category: Tim barrel]]
+

Current revision

Structure of the H258Y mutant of the phosphatidylinositol-specific phospholipase C from Staphylococcus aureus

PDB ID 4i9t

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4i9t"
Personal tools