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4irb
From Proteopedia
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| - | {{STRUCTURE_4irb| PDB=4irb | SCENE= }} | ||
| - | ===Crystal Structure of Vaccinia Virus Uracil DNA Glycosylase Mutant del171-172D4=== | ||
| - | {{ABSTRACT_PUBMED_23519808}} | ||
| - | == | + | ==Crystal Structure of Vaccinia Virus Uracil DNA Glycosylase Mutant del171-172D4== |
| - | [[ | + | <StructureSection load='4irb' size='340' side='right'caption='[[4irb]], [[Resolution|resolution]] 2.30Å' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[4irb]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaccinia_virus_Western_Reserve Vaccinia virus Western Reserve]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IRB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IRB FirstGlance]. <br> |
| - | [[4irb]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IRB OCA]. | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4irb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4irb OCA], [https://pdbe.org/4irb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4irb RCSB], [https://www.ebi.ac.uk/pdbsum/4irb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4irb ProSAT]</span></td></tr> | |
| - | < | + | </table> |
| - | [[ | + | == Function == |
| - | [ | + | [https://www.uniprot.org/uniprot/UNG_VACCW UNG_VACCW] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. Also part of a heterodimeric processivity factor which potentiates the DNA polymerase activity. Binds to DNA (By similarity). |
| - | [ | + | __TOC__ |
| - | + | </StructureSection> | |
| - | [ | + | [[Category: Large Structures]] |
| - | [ | + | [[Category: Vaccinia virus Western Reserve]] |
| - | [ | + | [[Category: Chattopadhyay D]] |
| - | [[Category: | + | [[Category: Nuth M]] |
| - | [[Category: | + | [[Category: Ricciardi RP]] |
| - | [[Category: | + | [[Category: Sartmatova D]] |
| - | [[Category: | + | [[Category: Schormann N]] |
| - | [[Category: | + | [[Category: Zhukovskaya N]] |
| - | [[Category: | + | |
| - | [[Category: | + | |
| - | [[Category: | + | |
Current revision
Crystal Structure of Vaccinia Virus Uracil DNA Glycosylase Mutant del171-172D4
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