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4iu0

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==Crystal structure of Leishmania mexicana arginase in complex with inhibitor ABH==
==Crystal structure of Leishmania mexicana arginase in complex with inhibitor ABH==
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<StructureSection load='4iu0' size='340' side='right' caption='[[4iu0]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
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<StructureSection load='4iu0' size='340' side='right'caption='[[4iu0]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4iu0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Leishmania_mexicana Leishmania mexicana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IU0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IU0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4iu0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_mexicana Leishmania mexicana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IU0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IU0 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ABH:2(S)-AMINO-6-BORONOHEXANOIC+ACID'>ABH</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.77&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ity|4ity]], [[2aeb|2aeb]], [[4iu1|4iu1]], [[4iu4|4iu4]], [[4iu5|4iu5]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ABH:2(S)-AMINO-6-BORONOHEXANOIC+ACID'>ABH</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ARG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5665 Leishmania mexicana])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4iu0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iu0 OCA], [https://pdbe.org/4iu0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4iu0 RCSB], [https://www.ebi.ac.uk/pdbsum/4iu0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4iu0 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Arginase Arginase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.3.1 3.5.3.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4iu0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iu0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4iu0 RCSB], [http://www.ebi.ac.uk/pdbsum/4iu0 PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q6TUJ5_LEIME Q6TUJ5_LEIME]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4iu0" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Arginase 3D structures|Arginase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Arginase]]
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[[Category: Large Structures]]
[[Category: Leishmania mexicana]]
[[Category: Leishmania mexicana]]
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[[Category: Antonio, E L.D]]
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[[Category: Christianson DW]]
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[[Category: Christianson, D W]]
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[[Category: D'Antonio EL]]
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[[Category: Dixit, U Gaur]]
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[[Category: Gaur Dixit U]]
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[[Category: Hai, Y]]
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[[Category: Hai Y]]
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[[Category: Roberts, S C]]
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[[Category: Roberts SC]]
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[[Category: Ullman, B]]
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[[Category: Ullman B]]
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[[Category: Wilson, M E]]
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[[Category: Wilson ME]]
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[[Category: Arginase fold]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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Current revision

Crystal structure of Leishmania mexicana arginase in complex with inhibitor ABH

PDB ID 4iu0

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