This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4ixd
From Proteopedia
(Difference between revisions)
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
==X-ray structure of lfa-1 i-domain in complex with ibe-667 at 1.8a resolution== | ==X-ray structure of lfa-1 i-domain in complex with ibe-667 at 1.8a resolution== | ||
| - | <StructureSection load='4ixd' size='340' side='right' caption='[[4ixd]], [[Resolution|resolution]] 1.80Å' scene=''> | + | <StructureSection load='4ixd' size='340' side='right'caption='[[4ixd]], [[Resolution|resolution]] 1.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4ixd]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4ixd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IXD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IXD FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1HV:4-(3-{4-[(3-AMINOPROPYL)CARBAMOYL]PHENYL}-1H-INDAZOL-1-YL)-N-METHYLBENZAMIDE'>1HV</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1HV:4-(3-{4-[(3-AMINOPROPYL)CARBAMOYL]PHENYL}-1H-INDAZOL-1-YL)-N-METHYLBENZAMIDE'>1HV</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ixd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ixd OCA], [https://pdbe.org/4ixd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ixd RCSB], [https://www.ebi.ac.uk/pdbsum/4ixd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ixd ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/ITAL_HUMAN ITAL_HUMAN] Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. |
==See Also== | ==See Also== | ||
| - | *[[Integrin|Integrin]] | + | *[[Integrin 3D structures|Integrin 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Kallen J]] |
| - | + | ||
| - | + | ||
Current revision
X-ray structure of lfa-1 i-domain in complex with ibe-667 at 1.8a resolution
| |||||||||||
