This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4j2t

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:35, 20 September 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 3: Line 3:
<StructureSection load='4j2t' size='340' side='right'caption='[[4j2t]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
<StructureSection load='4j2t' size='340' side='right'caption='[[4j2t]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4j2t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J2T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4J2T FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4j2t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J2T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J2T FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1HT:(3S,3AR,4S,6S,6AR,7S,8S,9BS)-6-(ACETYLOXY)-3A,4-BIS(BUTANOYLOXY)-3-HYDROXY-3,6,9-TRIMETHYL-8-{[(2E)-2-METHYLBUT-2-ENOYL]OXY}-2-OXO-2,3,3A,4,5,6,6A,7,8,9B-DECAHYDROAZULENO[4,5-B]FURAN-7-YL+OCTANOATE'>1HT</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PTY:PHOSPHATIDYLETHANOLAMINE'>PTY</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3nal|3nal]], [[3nan|3nan]], [[3nam|3nam]], [[2c8k|2c8k]], [[3n5k|3n5k]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1HT:(3S,3AR,4S,6S,6AR,7S,8S,9BS)-6-(ACETYLOXY)-3A,4-BIS(BUTANOYLOXY)-3-HYDROXY-3,6,9-TRIMETHYL-8-{[(2E)-2-METHYLBUT-2-ENOYL]OXY}-2-OXO-2,3,3A,4,5,6,6A,7,8,9B-DECAHYDROAZULENO[4,5-B]FURAN-7-YL+OCTANOATE'>1HT</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PTY:PHOSPHATIDYLETHANOLAMINE'>PTY</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calcium-transporting_ATPase Calcium-transporting ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.8 3.6.3.8] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j2t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j2t OCA], [https://pdbe.org/4j2t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j2t RCSB], [https://www.ebi.ac.uk/pdbsum/4j2t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j2t ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4j2t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j2t OCA], [http://pdbe.org/4j2t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4j2t RCSB], [http://www.ebi.ac.uk/pdbsum/4j2t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4j2t ProSAT]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/AT2A1_RABIT AT2A1_RABIT] This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 25: Line 26:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Calcium-transporting ATPase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
-
[[Category: Autzen, H E]]
+
[[Category: Autzen HE]]
-
[[Category: Bonde, D F]]
+
[[Category: Bonde DF]]
-
[[Category: Bublitz, M]]
+
[[Category: Bublitz M]]
-
[[Category: Christensen, S B]]
+
[[Category: Christensen SB]]
-
[[Category: Dach, I]]
+
[[Category: Dach I]]
-
[[Category: Lie, M A]]
+
[[Category: Lie MA]]
-
[[Category: Liu, H]]
+
[[Category: Liu H]]
-
[[Category: Moller, J V]]
+
[[Category: Moller JV]]
-
[[Category: Nissen, P]]
+
[[Category: Nissen P]]
-
[[Category: Olesen, C]]
+
[[Category: Olesen C]]
-
[[Category: Paulsen, E S]]
+
[[Category: Paulsen ES]]
-
[[Category: Schiott, B]]
+
[[Category: Schiott B]]
-
[[Category: Sehgal, P]]
+
[[Category: Sehgal P]]
-
[[Category: Tenori, E]]
+
[[Category: Tenori E]]
-
[[Category: Villadsen, J]]
+
[[Category: Villadsen J]]
-
[[Category: Calcium transport]]
+
-
[[Category: Hydrolase-hydrolase inhibitor complex]]
+
-
[[Category: P-type atpase]]
+
-
[[Category: Thapsigargin analog]]
+

Current revision

Inhibitor-bound Ca2+ ATPase

PDB ID 4j2t

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4j2t"
Personal tools