4j5y

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==Crystal structure of Hfq from Pseudomonas aeruginosa in complex with ATP==
==Crystal structure of Hfq from Pseudomonas aeruginosa in complex with ATP==
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<StructureSection load='4j5y' size='340' side='right' caption='[[4j5y]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='4j5y' size='340' side='right'caption='[[4j5y]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4j5y]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J5Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4J5Y FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4j5y]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J5Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J5Y FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.0953&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1u1s|1u1s]], [[1u1t|1u1t]], [[3qui|3qui]], [[3gib|3gib]], [[3rer|3rer]], [[3qo3|3qo3]], [[4j6w|4j6w]], [[4j6x|4j6x]], [[4j6y|4j6y]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hfq, PA4944 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 Pseudomonas aeruginosa PAO1])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j5y OCA], [https://pdbe.org/4j5y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j5y RCSB], [https://www.ebi.ac.uk/pdbsum/4j5y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j5y ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4j5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j5y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4j5y RCSB], [http://www.ebi.ac.uk/pdbsum/4j5y PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/HFQ_PSEAE HFQ_PSEAE]] RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity).
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[https://www.uniprot.org/uniprot/HFQ_PSEAE HFQ_PSEAE] RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 4j5y" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Protein Hfq 3D structures|Protein Hfq 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Pseudomonas aeruginosa pao1]]
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[[Category: Large Structures]]
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[[Category: Lekontseva, N]]
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[[Category: Pseudomonas aeruginosa PAO1]]
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[[Category: Murina, V]]
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[[Category: Lekontseva N]]
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[[Category: Nikulin, A]]
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[[Category: Murina V]]
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[[Category: Lsm]]
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[[Category: Nikulin A]]
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[[Category: Mrna]]
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[[Category: Rna binding protein]]
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[[Category: Rna chaperone]]
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[[Category: Srna]]
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Current revision

Crystal structure of Hfq from Pseudomonas aeruginosa in complex with ATP

PDB ID 4j5y

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