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4jga

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==X-ray crystal structure of 3-oxoacyl-[acyl-carrier-protein] synthase 2 from Rickettsia rickettsii==
==X-ray crystal structure of 3-oxoacyl-[acyl-carrier-protein] synthase 2 from Rickettsia rickettsii==
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<StructureSection load='4jga' size='340' side='right' caption='[[4jga]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='4jga' size='340' side='right'caption='[[4jga]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4jga]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ricrs Ricrs]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JGA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JGA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4jga]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rickettsia_rickettsii_str._'Sheila_Smith' Rickettsia rickettsii str. 'Sheila Smith']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JGA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JGA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">A1G_06510 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=392021 RICRS])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-ketoacyl-[acyl-carrier-protein]_synthase_II Beta-ketoacyl-[acyl-carrier-protein] synthase II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.179 2.3.1.179] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jga FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jga OCA], [https://pdbe.org/4jga PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jga RCSB], [https://www.ebi.ac.uk/pdbsum/4jga PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jga ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jga FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jga OCA], [http://pdbe.org/4jga PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4jga RCSB], [http://www.ebi.ac.uk/pdbsum/4jga PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4jga ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/A8GTN0_RICRS A8GTN0_RICRS]] catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-acp (by similarity)
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[https://www.uniprot.org/uniprot/A0A0H3AY56_RICRS A0A0H3AY56_RICRS] Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.[PIRNR:PIRNR000447]
==See Also==
==See Also==
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*[[Acyl carrier protein synthase|Acyl carrier protein synthase]]
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*[[Acyl carrier protein synthase 3D structures|Acyl carrier protein synthase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ricrs]]
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[[Category: Large Structures]]
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[[Category: Structural genomic]]
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[[Category: Rickettsia rickettsii str. 'Sheila Smith']]
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[[Category: Synthase]]
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[[Category: Transferase]]
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Current revision

X-ray crystal structure of 3-oxoacyl-[acyl-carrier-protein] synthase 2 from Rickettsia rickettsii

PDB ID 4jga

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