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4juu

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(New page: '''Unreleased structure''' The entry 4juu is ON HOLD Authors: Vetting, M.W., Toro, R., Bhosle, R., Al Obaidi, N.F., Morisco, L.L., Wasserman, S.R., Sojitra, S., Washington, E., Scott Gl...)
Current revision (15:49, 20 September 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 4juu is ON HOLD
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==Crystal structure of a putative hydroxyproline epimerase from xanthomonas campestris (TARGET EFI-506516) with bound phosphate and unknown ligand==
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<StructureSection load='4juu' size='340' side='right'caption='[[4juu]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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Authors: Vetting, M.W., Toro, R., Bhosle, R., Al Obaidi, N.F., Morisco, L.L., Wasserman, S.R., Sojitra, S., Washington, E., Scott Glenn, A., Chowdhury, S., Evans, B., Hammonds, J., Stead, M., Hillerich, B., Love, J., Seidel, R.D., Imker, H.J., Gerlt, J.A., Almo, S.C., Enzyme Function Initiative (EFI)
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4juu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Xanthomonas_campestris_pv._campestris_str._ATCC_33913 Xanthomonas campestris pv. campestris str. ATCC 33913]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JUU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JUU FirstGlance]. <br>
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Description: Crystal structure of a putative hydroxyproline epimerase from xanthomonas campestris (TARGET EFI-506516) with bound phosphate and unknown ligand
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4juu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4juu OCA], [https://pdbe.org/4juu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4juu RCSB], [https://www.ebi.ac.uk/pdbsum/4juu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4juu ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/4HYPE_XANCP 4HYPE_XANCP] Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp). Is likely involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate. Can also catalyze the epimerization of trans-3-hydroxy-L-proline (t3LHyp) to cis-3-hydroxy-D-proline (c3DHyp), albeit with 500-fold lower efficiency. Displays no proline racemase activity.<ref>PMID:24980702</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Xanthomonas campestris pv. campestris str. ATCC 33913]]
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[[Category: Al Obaidi NF]]
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[[Category: Almo SC]]
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[[Category: Bhosle R]]
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[[Category: Chowdhury S]]
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[[Category: Evans B]]
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[[Category: Gerlt JA]]
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[[Category: Hammonds J]]
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[[Category: Hillerich B]]
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[[Category: Imker HJ]]
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[[Category: Love J]]
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[[Category: Morisco LL]]
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[[Category: Scott Glenn A]]
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[[Category: Seidel RD]]
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[[Category: Sojitra S]]
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[[Category: Stead M]]
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[[Category: Toro R]]
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[[Category: Vetting MW]]
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[[Category: Washington E]]
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[[Category: Wasserman SR]]

Current revision

Crystal structure of a putative hydroxyproline epimerase from xanthomonas campestris (TARGET EFI-506516) with bound phosphate and unknown ligand

PDB ID 4juu

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