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4k6l

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==Structure of Typhoid Toxin==
==Structure of Typhoid Toxin==
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<StructureSection load='4k6l' size='340' side='right' caption='[[4k6l]], [[Resolution|resolution]] 2.39&Aring;' scene=''>
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<StructureSection load='4k6l' size='340' side='right'caption='[[4k6l]], [[Resolution|resolution]] 2.39&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4k6l]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_typhi"_schroeter_1886 "bacillus typhi" schroeter 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K6L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K6L FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4k6l]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhi Salmonella enterica subsp. enterica serovar Typhi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K6L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K6L FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.393&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">STY1891, t1107 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90370 "Bacillus typhi" Schroeter 1886]), cdtB, STY1886, t1111 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90370 "Bacillus typhi" Schroeter 1886]), STY1890, t1108 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90370 "Bacillus typhi" Schroeter 1886])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k6l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k6l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k6l RCSB], [http://www.ebi.ac.uk/pdbsum/4k6l PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k6l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k6l OCA], [https://pdbe.org/4k6l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k6l RCSB], [https://www.ebi.ac.uk/pdbsum/4k6l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k6l ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CDTB_SALTI CDTB_SALTI]] Produces a CDT (cytolethal distending toxin) activity, which causes DNA damage in intoxicated cells. This damage induces G2/M cell cycle arrest, chromatin fragmentation, cell distention and nucleus enlargement.
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[https://www.uniprot.org/uniprot/Q8Z6A3_SALTI Q8Z6A3_SALTI]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4k6l" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus typhi schroeter 1886]]
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[[Category: Large Structures]]
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[[Category: Galan, J]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhi]]
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[[Category: Gao, X]]
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[[Category: Galan J]]
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[[Category: Song, J]]
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[[Category: Gao X]]
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[[Category: Bacterial toxin]]
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[[Category: Song J]]
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[[Category: Complex]]
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[[Category: Sugar]]
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[[Category: Toxin]]
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Current revision

Structure of Typhoid Toxin

PDB ID 4k6l

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