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4k7x
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==Crystal structure of a 4-hydroxyproline epimerase from burkholderia multivorans, target efi-506479, with bound phosphate, closed domains== | ==Crystal structure of a 4-hydroxyproline epimerase from burkholderia multivorans, target efi-506479, with bound phosphate, closed domains== | ||
| - | <StructureSection load='4k7x' size='340' side='right' caption='[[4k7x]], [[Resolution|resolution]] 1.75Å' scene=''> | + | <StructureSection load='4k7x' size='340' side='right'caption='[[4k7x]], [[Resolution|resolution]] 1.75Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4k7x]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4k7x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_multivorans_ATCC_17616 Burkholderia multivorans ATCC 17616]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K7X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K7X FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k7x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k7x OCA], [https://pdbe.org/4k7x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k7x RCSB], [https://www.ebi.ac.uk/pdbsum/4k7x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k7x ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/4HPE1_BURM1 4HPE1_BURM1] Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp). Is likely involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate. Displays no proline racemase activity.<ref>PMID:24980702</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Burkholderia multivorans | + | [[Category: Burkholderia multivorans ATCC 17616]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Al Obaidi NF]] |
| - | [[Category: | + | [[Category: Almo SC]] |
| - | [[Category: | + | [[Category: Bhosle R]] |
| - | [[Category: | + | [[Category: Chowdhury S]] |
| - | [[Category: Evans | + | [[Category: Evans B]] |
| - | [[Category: Gerlt | + | [[Category: Gerlt JA]] |
| - | + | [[Category: Hammonds J]] | |
| - | [[Category: Hammonds | + | [[Category: Hillerich B]] |
| - | [[Category: Hillerich | + | [[Category: Imker HJ]] |
| - | [[Category: Imker | + | [[Category: Love J]] |
| - | [[Category: Love | + | [[Category: Morisco LL]] |
| - | [[Category: Morisco | + | [[Category: Scott Glenn A]] |
| - | [[Category: | + | [[Category: Seidel RD]] |
| - | [[Category: Seidel | + | [[Category: Sojitra S]] |
| - | [[Category: Sojitra | + | [[Category: Stead M]] |
| - | [[Category: Stead | + | [[Category: Toro R]] |
| - | [[Category: Toro | + | [[Category: Vetting MW]] |
| - | [[Category: Vetting | + | [[Category: Washington E]] |
| - | [[Category: Washington | + | [[Category: Wasserman SR]] |
| - | [[Category: Wasserman | + | |
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Current revision
Crystal structure of a 4-hydroxyproline epimerase from burkholderia multivorans, target efi-506479, with bound phosphate, closed domains
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Categories: Burkholderia multivorans ATCC 17616 | Large Structures | Al Obaidi NF | Almo SC | Bhosle R | Chowdhury S | Evans B | Gerlt JA | Hammonds J | Hillerich B | Imker HJ | Love J | Morisco LL | Scott Glenn A | Seidel RD | Sojitra S | Stead M | Toro R | Vetting MW | Washington E | Wasserman SR
