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4kxl

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==Crystal structure of DNPH1 (RCL) with 6-CYCLOPENTYL-AMP==
==Crystal structure of DNPH1 (RCL) with 6-CYCLOPENTYL-AMP==
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<StructureSection load='4kxl' size='340' side='right' caption='[[4kxl]], [[Resolution|resolution]] 1.69&Aring;' scene=''>
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<StructureSection load='4kxl' size='340' side='right'caption='[[4kxl]], [[Resolution|resolution]] 1.69&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4kxl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KXL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KXL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4kxl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KXL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KXL FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6C6:N-CYCLOPENTYLADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>6C6</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.69&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4fyi|4fyi]], [[4kxm|4kxm]], [[4kxn|4kxn]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6C6:N-CYCLOPENTYLADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>6C6</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Dnph1, Rcl ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kxl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kxl OCA], [https://pdbe.org/4kxl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kxl RCSB], [https://www.ebi.ac.uk/pdbsum/4kxl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kxl ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kxl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kxl OCA], [http://pdbe.org/4kxl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4kxl RCSB], [http://www.ebi.ac.uk/pdbsum/4kxl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4kxl ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DNPH1_RAT DNPH1_RAT]] Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.<ref>PMID:17234634</ref>
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[https://www.uniprot.org/uniprot/DNPH1_RAT DNPH1_RAT] Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.<ref>PMID:17234634</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Buffalo rat]]
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[[Category: Large Structures]]
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[[Category: Kaminski, P A]]
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[[Category: Rattus norvegicus]]
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[[Category: Labesse, G]]
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[[Category: Kaminski PA]]
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[[Category: Padilla, A]]
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[[Category: Labesse G]]
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[[Category: Deoxyribonucleoside 5'-monophosphate n-glycosidase]]
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[[Category: Padilla A]]
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[[Category: Hydrolase]]
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Current revision

Crystal structure of DNPH1 (RCL) with 6-CYCLOPENTYL-AMP

PDB ID 4kxl

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