This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4kxw

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (16:06, 20 September 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 3: Line 3:
<StructureSection load='4kxw' size='340' side='right'caption='[[4kxw]], [[Resolution|resolution]] 0.97&Aring;' scene=''>
<StructureSection load='4kxw' size='340' side='right'caption='[[4kxw]], [[Resolution|resolution]] 0.97&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4kxw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KXW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KXW FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4kxw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KXW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KXW FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DX5:D-XYLITOL-5-PHOSPHATE'>DX5</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TPP:THIAMINE+DIPHOSPHATE'>TPP</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.97&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TKT ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DX5:D-XYLITOL-5-PHOSPHATE'>DX5</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TPP:THIAMINE+DIPHOSPHATE'>TPP</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Transketolase Transketolase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.2.1.1 2.2.1.1] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kxw OCA], [https://pdbe.org/4kxw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kxw RCSB], [https://www.ebi.ac.uk/pdbsum/4kxw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kxw ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kxw OCA], [https://pdbe.org/4kxw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kxw RCSB], [https://www.ebi.ac.uk/pdbsum/4kxw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kxw ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/TKT_HUMAN TKT_HUMAN]] Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
+
[https://www.uniprot.org/uniprot/TKT_HUMAN TKT_HUMAN] Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 22: Line 21:
==See Also==
==See Also==
-
*[[Transketolase|Transketolase]]
+
*[[Transketolase 3D structures|Transketolase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Transketolase]]
+
[[Category: Ficner R]]
-
[[Category: Ficner, R]]
+
[[Category: Luedtke S]]
-
[[Category: Luedtke, S]]
+
[[Category: Neumann P]]
-
[[Category: Neumann, P]]
+
[[Category: Tittmann K]]
-
[[Category: Tittmann, K]]
+
-
[[Category: Enzyme catalysis]]
+
-
[[Category: Pentose phosphate pathway]]
+
-
[[Category: Thiamin diphosphate]]
+
-
[[Category: Transferase]]
+

Current revision

Human transketolase in covalent complex with donor ketose D-xylulose-5-phosphate, crystal 2

PDB ID 4kxw

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4kxw"
Personal tools