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4lt1

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<StructureSection load='4lt1' size='340' side='right'caption='[[4lt1]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='4lt1' size='340' side='right'caption='[[4lt1]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4lt1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LT1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LT1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4lt1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LT1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LT1 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=QPT:CARBOPLATIN'>QPT</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4dd7|4dd7]], [[4dd9|4dd9]], [[4g4c|4g4c]], [[4lt0|4lt0]], [[4lt2|4lt2]], [[4lt3|4lt3]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=QPT:CARBOPLATIN'>QPT</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lt1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lt1 OCA], [https://pdbe.org/4lt1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lt1 RCSB], [https://www.ebi.ac.uk/pdbsum/4lt1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lt1 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lt1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lt1 OCA], [http://pdbe.org/4lt1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lt1 RCSB], [http://www.ebi.ac.uk/pdbsum/4lt1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lt1 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
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[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
==See Also==
==See Also==
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[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lysozyme]]
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[[Category: Diederichs K]]
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[[Category: Diederichs, K]]
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[[Category: Helliwell JR]]
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[[Category: Helliwell, J R]]
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[[Category: Kroon-Batenburg LMJ]]
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[[Category: Kroon-Batenburg, L M.J]]
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[[Category: Schreurs AMM]]
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[[Category: Schreurs, A M.M]]
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[[Category: Tanley SWM]]
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[[Category: Tanley, S W.M]]
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[[Category: Avoid partial conversion to cisplatin]]
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[[Category: Dpi]]
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[[Category: Glycosyl hydrolase]]
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[[Category: Histidine]]
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[[Category: Hydrolase]]
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[[Category: Mpd]]
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[[Category: Pair-wise refinement technique]]
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[[Category: Resolution limit choice]]
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Current revision

HEWL co-crystallised with Carboplatin in non-NaCl conditions: crystal 1 processed using the XDS software package

PDB ID 4lt1

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