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4lt6

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==Crystal Structure of human poly(A) polymerase gamma==
==Crystal Structure of human poly(A) polymerase gamma==
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<StructureSection load='4lt6' size='340' side='right' caption='[[4lt6]], [[Resolution|resolution]] 2.79&Aring;' scene=''>
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<StructureSection load='4lt6' size='340' side='right'caption='[[4lt6]], [[Resolution|resolution]] 2.79&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4lt6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LT6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LT6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4lt6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LT6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LT6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3AT:3-DEOXYADENOSINE-5-TRIPHOSPHATE'>3AT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.79&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PAPOLG, PAP2, PAPG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3AT:3-DEOXYADENOSINE-5-TRIPHOSPHATE'>3AT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Polynucleotide_adenylyltransferase Polynucleotide adenylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.19 2.7.7.19] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lt6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lt6 OCA], [https://pdbe.org/4lt6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lt6 RCSB], [https://www.ebi.ac.uk/pdbsum/4lt6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lt6 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lt6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lt6 OCA], [http://pdbe.org/4lt6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lt6 RCSB], [http://www.ebi.ac.uk/pdbsum/4lt6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lt6 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PAPOG_HUMAN PAPOG_HUMAN]] Responsible for the post-transcriptional adenylation of the 3'-terminal of mRNA precursors and several small RNAs including signal recognition particle (SRP) RNA, nuclear 7SK RNA, U2 small nuclear RNA, and ribosomal 5S RNA.
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[https://www.uniprot.org/uniprot/PAPOG_HUMAN PAPOG_HUMAN] Responsible for the post-transcriptional adenylation of the 3'-terminal of mRNA precursors and several small RNAs including signal recognition particle (SRP) RNA, nuclear 7SK RNA, U2 small nuclear RNA, and ribosomal 5S RNA.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Poly(A) Polymerase|Poly(A) Polymerase]]
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*[[Poly(A) polymerase 3D structures|Poly(A) polymerase 3D structures]]
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*[[RNA polymerase|RNA polymerase]]
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== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Polynucleotide adenylyltransferase]]
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[[Category: Large Structures]]
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[[Category: Doublie, S]]
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[[Category: Doublie S]]
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[[Category: Keller, W]]
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[[Category: Keller W]]
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[[Category: Martin, G]]
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[[Category: Martin G]]
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[[Category: Nausch, L]]
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[[Category: Nausch L]]
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[[Category: Yang, Q]]
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[[Category: Yang Q]]
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[[Category: 3' processing]]
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[[Category: Mrna processing]]
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[[Category: Nucleus]]
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[[Category: Pap]]
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[[Category: Polyadenylation]]
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[[Category: Polymerase]]
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[[Category: Transferase]]
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Current revision

Crystal Structure of human poly(A) polymerase gamma

PDB ID 4lt6

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