4lts

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4lts]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LTS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LTS FirstGlance]. <br>
<table><tr><td colspan='2'>[[4lts]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LTS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LTS FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=LTS:2-CYANO-1-PYRIDIN-4-YL-3-(4-{[3-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}BENZYL)GUANIDINE'>LTS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.692&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=LTS:2-CYANO-1-PYRIDIN-4-YL-3-(4-{[3-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}BENZYL)GUANIDINE'>LTS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lts FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lts OCA], [https://pdbe.org/4lts PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lts RCSB], [https://www.ebi.ac.uk/pdbsum/4lts PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lts ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lts FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lts OCA], [https://pdbe.org/4lts PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lts RCSB], [https://www.ebi.ac.uk/pdbsum/4lts PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lts ProSAT]</span></td></tr>
</table>
</table>

Current revision

Discovery of Potent and Efficacious Cyanoguanidine-containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors

PDB ID 4lts

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