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4m8d
From Proteopedia
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==Crystal structure of an isatin hydrolase bound to product analogue thioisatinate== | ==Crystal structure of an isatin hydrolase bound to product analogue thioisatinate== | ||
| - | <StructureSection load='4m8d' size='340' side='right' caption='[[4m8d]], [[Resolution|resolution]] 1.90Å' scene=''> | + | <StructureSection load='4m8d' size='340' side='right'caption='[[4m8d]], [[Resolution|resolution]] 1.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4m8d]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M8D OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4m8d]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Roseibium_aggregatum_IAM_12614 Roseibium aggregatum IAM 12614]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M8D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M8D FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=23J:OXO(2-SULFANYLPHENYL)ACETIC+ACID'>23J</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=23J:OXO(2-SULFANYLPHENYL)ACETIC+ACID'>23J</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m8d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m8d OCA], [https://pdbe.org/4m8d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m8d RCSB], [https://www.ebi.ac.uk/pdbsum/4m8d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m8d ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ISAHY_ROSAI ISAHY_ROSAI] Involved in the degradation of the plant hormone indole-3-acetic acid (IAA). Catalyzes the hydrolysis of the cyclic amide bond (lactam) of isatin (1H-indole-2,3-dione) to yield isatinate (2-(2-aminophenyl)-2-oxoacetate).<ref>PMID:24917679</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4m8d" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Roseibium aggregatum IAM 12614]] |
| - | [[Category: | + | [[Category: Bjerregaard-Andersen K]] |
| - | [[Category: | + | [[Category: Etzerodt M]] |
| - | [[Category: | + | [[Category: Jensen JK]] |
| - | [[Category: | + | [[Category: Jochimsen B]] |
| - | [[Category: | + | [[Category: Morth JP]] |
| - | [[Category: | + | [[Category: Sommer T]] |
Current revision
Crystal structure of an isatin hydrolase bound to product analogue thioisatinate
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