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4mc8

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==Hedycaryol synthase in complex with HEPES==
==Hedycaryol synthase in complex with HEPES==
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<StructureSection load='4mc8' size='340' side='right' caption='[[4mc8]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<StructureSection load='4mc8' size='340' side='right'caption='[[4mc8]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4mc8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Kitsk Kitsk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MC8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MC8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4mc8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Kitasatospora_setae_KM-6054 Kitasatospora setae KM-6054]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MC8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MC8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1hm4|1hm4]], [[4mc0|4mc0]], [[4mc3|4mc3]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KSE_00200t, KSE_76540t ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=452652 KITSK])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mc8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mc8 OCA], [https://pdbe.org/4mc8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mc8 RCSB], [https://www.ebi.ac.uk/pdbsum/4mc8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mc8 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mc8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mc8 OCA], [http://pdbe.org/4mc8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mc8 RCSB], [http://www.ebi.ac.uk/pdbsum/4mc8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mc8 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HCS_KITSK HCS_KITSK] Catalyzes the conversion of (2E,6E)-farnesyl diphosphate (FPP) into (2Z,6E)-hedycaryol via a 1,11-cyclization.<ref>PMID:24399794</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Kitsk]]
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[[Category: Kitasatospora setae KM-6054]]
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[[Category: Baer, P]]
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[[Category: Large Structures]]
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[[Category: Cirton, C]]
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[[Category: Baer P]]
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[[Category: Dickschat, J]]
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[[Category: Cirton C]]
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[[Category: Groll, M]]
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[[Category: Dickschat J]]
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[[Category: Kaufmann, N]]
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[[Category: Groll M]]
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[[Category: Mann, C Oliveira]]
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[[Category: Kaufmann N]]
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[[Category: Rabe, P]]
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[[Category: Oliveira Mann C]]
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[[Category: Cyclase]]
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[[Category: Rabe P]]
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[[Category: Helix break]]
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[[Category: Helix dipol]]
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[[Category: Lyase]]
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[[Category: Terpene alpha domain class i]]
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[[Category: Terpenoid]]
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Current revision

Hedycaryol synthase in complex with HEPES

PDB ID 4mc8

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