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4mhl

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==The crystal structure of human interleukin-11==
==The crystal structure of human interleukin-11==
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<StructureSection load='4mhl' size='340' side='right' caption='[[4mhl]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
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<StructureSection load='4mhl' size='340' side='right'caption='[[4mhl]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4mhl]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MHL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MHL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4mhl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MHL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MHL FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARF:FORMAMIDE'>ARF</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.09&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mhl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mhl OCA], [http://pdbe.org/4mhl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mhl RCSB], [http://www.ebi.ac.uk/pdbsum/4mhl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mhl ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARF:FORMAMIDE'>ARF</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mhl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mhl OCA], [https://pdbe.org/4mhl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mhl RCSB], [https://www.ebi.ac.uk/pdbsum/4mhl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mhl ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/IL11_HUMAN IL11_HUMAN]] Directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production.
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[https://www.uniprot.org/uniprot/IL11_HUMAN IL11_HUMAN] Directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Interleukin|Interleukin]]
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*[[Interleukin 3D structures|Interleukin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Griffin, M D.W]]
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[[Category: Homo sapiens]]
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[[Category: Cytokine]]
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[[Category: Large Structures]]
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[[Category: Four-helix bundle]]
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[[Category: Griffin MDW]]
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[[Category: Growth factor]]
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[[Category: Interleukin-11 receptor subunit alpha]]
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[[Category: Long-chain helical cytokine]]
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[[Category: Membrane glycoprotein 130]]
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[[Category: Protein binding]]
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[[Category: Secreted]]
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Current revision

The crystal structure of human interleukin-11

PDB ID 4mhl

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