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4mpg
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==Crystal structure of human glutathione transferase theta-2, complex with glutathione and unknown ligand, target EFI-507257== | ==Crystal structure of human glutathione transferase theta-2, complex with glutathione and unknown ligand, target EFI-507257== | ||
| - | <StructureSection load='4mpg' size='340' side='right' caption='[[4mpg]], [[Resolution|resolution]] 1.95Å' scene=''> | + | <StructureSection load='4mpg' size='340' side='right'caption='[[4mpg]], [[Resolution|resolution]] 1.95Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4mpg]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4mpg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MPG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MPG FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.951Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mpg OCA], [https://pdbe.org/4mpg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mpg RCSB], [https://www.ebi.ac.uk/pdbsum/4mpg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mpg ProSAT]</span></td></tr> | |
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/GSTT2_HUMAN GSTT2_HUMAN] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity. |
==See Also== | ==See Also== | ||
| - | *[[Glutathione S-transferase|Glutathione S-transferase]] | + | *[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Glutathione transferase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Al Obaidi N]] |
| - | [[Category: | + | [[Category: Almo SC]] |
| - | [[Category: | + | [[Category: Armstrong RN]] |
| - | [[Category: | + | [[Category: Bhosle R]] |
| - | [[Category: | + | [[Category: Chowdhury S]] |
| - | [[Category: | + | [[Category: Evans B]] |
| - | [[Category: | + | [[Category: Gerlt JA]] |
| - | [[Category: Hammonds | + | [[Category: Hammonds J]] |
| - | [[Category: Hillerich | + | [[Category: Hillerich B]] |
| - | [[Category: Imker | + | [[Category: Imker HJ]] |
| - | [[Category: Love | + | [[Category: Love J]] |
| - | [[Category: | + | [[Category: Patskovsky Y]] |
| - | [[Category: | + | [[Category: Scott Glenn A]] |
| - | [[Category: Seidel | + | [[Category: Seidel RD]] |
| - | [[Category: Stead | + | [[Category: Stead M]] |
| - | [[Category: Toro | + | [[Category: Toro R]] |
| - | [[Category: Washington | + | [[Category: Washington E]] |
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Current revision
Crystal structure of human glutathione transferase theta-2, complex with glutathione and unknown ligand, target EFI-507257
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Categories: Homo sapiens | Large Structures | Al Obaidi N | Almo SC | Armstrong RN | Bhosle R | Chowdhury S | Evans B | Gerlt JA | Hammonds J | Hillerich B | Imker HJ | Love J | Patskovsky Y | Scott Glenn A | Seidel RD | Stead M | Toro R | Washington E
