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4n5u

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'''Unreleased structure'''
 
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The entry 4n5u is ON HOLD
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==Crystal structure of the 4th FN3 domain of human Protein Tyrosine phosphatase, receptor type F [PSI-NYSGRC-006240]==
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<StructureSection load='4n5u' size='340' side='right'caption='[[4n5u]], [[Resolution|resolution]] 1.46&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4n5u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N5U FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.456&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n5u OCA], [https://pdbe.org/4n5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n5u RCSB], [https://www.ebi.ac.uk/pdbsum/4n5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n5u ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PTPRF_HUMAN PTPRF_HUMAN] Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase).<ref>PMID:10338209</ref> The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one.<ref>PMID:10338209</ref>
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Authors: Kumar, P.R., Banu, R., Bhosle, R., Calarese, D.A., Celikgil, A., Chamala, S., Chan, M.K., Chowdhury, S., Fiser, A., Garforth, S.J., Glenn, A.S., Hillerich, B., Khafizov, K., Attonito, J., Love, J.D., Patel, H., Patel, R., Seidel, R.D., Smith, B., Stead, M., Toro, R., Casadevall, A., Almo, S.C., Immune Function Network (IFN) - New York Structural Genomics Consortium, New York Structural Genomics Research Consortium (NYSGRC)
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==See Also==
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*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]]
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Description: Crystal structure of the 4th FN3 domain of human Protein Tyrosine phosphatase, receptor type F [PSI-NYSGRC-006240]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Almo SC]]
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[[Category: Attonito J]]
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[[Category: Banu R]]
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[[Category: Bhosle R]]
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[[Category: Calarese DA]]
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[[Category: Casadevall A]]
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[[Category: Celikgil A]]
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[[Category: Chamala S]]
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[[Category: Chan MK]]
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[[Category: Chowdhury S]]
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[[Category: Fiser A]]
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[[Category: Garforth SJ]]
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[[Category: Glenn AS]]
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[[Category: Hillerich B]]
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[[Category: Khafizov K]]
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[[Category: Kumar PR]]
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[[Category: Love JD]]
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[[Category: Patel H]]
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[[Category: Patel R]]
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[[Category: Seidel RD]]
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[[Category: Smith B]]
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[[Category: Stead M]]
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[[Category: Toro R]]

Current revision

Crystal structure of the 4th FN3 domain of human Protein Tyrosine phosphatase, receptor type F [PSI-NYSGRC-006240]

PDB ID 4n5u

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